耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
透析中の上顎癌例に対する選択的動注化学療法の経験
鈴木 貴博志賀 清人小林 俊光
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2006 年 99 巻 6 号 p. 439-444

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When antineoplastic drugs are administered to a patient with impaired or unstable renal function, problems related to the dosage schedule may occur because of differences in pharmacokinetics between patients with normal renal function and those with renal dysfunction. We performed selective intraarterial infusion chemotherapy for a patient with maxillary squamous cell carcinoma who was undergoing hemodialysis for chronic renal failure. Cisplatin at doses of 50mg/body and docetaxel at doses of 20mg/body were administered via the maxillary artery twice at a one-week interval. The effect of intraarterial infusion chemotherapy was partial response. We could carry out the subsequential surgery and radiation therapy without severe adverse effects.

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