Insights into clinical diagnosis and treatment of malignant hepatic perivascular epithelioid cell tumor

Zhongyu Li; Yongzhi Zhou; Chaoqun Wang; Hongjun Yu; Guangchao Yang; Yong Ma

doi:10.5582/irdr.2022.01111

Communication

Insights into clinical diagnosis and treatment of malignant hepatic perivascular epithelioid cell tumor

Zhongyu Li, Yongzhi Zhou, Chaoqun Wang, Hongjun Yu, Guangchao Yang, Yong Ma

Author information

Zhongyu Li
Key Laboratory of Hepatosplenic Surgery, Ministry of Education, Harbin, Heilongjiang, China.
Department of Minimal Invasive Hepatic Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Yongzhi Zhou
Key Laboratory of Hepatosplenic Surgery, Ministry of Education, Harbin, Heilongjiang, China.
Department of Minimal Invasive Hepatic Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Chaoqun Wang
Key Laboratory of Hepatosplenic Surgery, Ministry of Education, Harbin, Heilongjiang, China.
Department of Minimal Invasive Hepatic Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Hongjun Yu
Key Laboratory of Hepatosplenic Surgery, Ministry of Education, Harbin, Heilongjiang, China.
Department of Minimal Invasive Hepatic Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Guangchao Yang
Key Laboratory of Hepatosplenic Surgery, Ministry of Education, Harbin, Heilongjiang, China.
Department of Minimal Invasive Hepatic Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Yong Ma
Key Laboratory of Hepatosplenic Surgery, Ministry of Education, Harbin, Heilongjiang, China.
Department of Minimal Invasive Hepatic Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.

Keywords: PEComa, liver tumor, hepatectomy, mTOR inhibitors, TFE3

JOURNAL FREE ACCESS

2022 Volume 11 Issue 4 Pages 202-205

DOI https://doi.org/10.5582/irdr.2022.01111

Browse “Advance online publication” version

Details

Abstract

Perivascular epithelioid cell tumors (PEComas) are infrequent mesenchymal tumors. They are usually benign, and only a few are malignant. These tumors are more commonly found in middle-aged women. PEComas are mainly composed of differentiated perivascular epithelioid cells arranged radially around the vascular cavity, and they are usually positive for melanocyte markers and smooth muscle cell differentiation markers. Among the PEComas, hepatic PEComas generally have no obvious symptoms and no typical imaging manifestations. Malignant hepatic PEComas are even rarer. So, we explained our insights into clinical diagnosis and treatment of malignant hepatic PEComas, in order to help clinicians and pathologists to further understand PEComas.

Corresponding author

Register with J-STAGE for free!