Spiroalkaloids and Coumarins from the Stem Bark of Pauridiantha callicarpoides

Ostend K. Tatuedom; Simeon F. Kouam; Diane Beatrice Yapna; Bonaventure T. Ngadjui; Ivan R. Green; M. Iqbal Choudhary; Jeanne E. R. Lantovololona; Michael Spiteller

doi:10.5560/znb.2014-4055

Published by De Gruyter June 2, 2014

Spiroalkaloids and Coumarins from the Stem Bark of Pauridiantha callicarpoides

Ostend K. Tatuedom , Simeon F. Kouam , Diane Beatrice Yapna , Bonaventure T. Ngadjui , Ivan R. Green , M. Iqbal Choudhary , Jeanne E. R. Lantovololona and Michael Spiteller

From the journal Zeitschrift für Naturforschung B

https://doi.org/10.5560/znb.2014-4055

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A new spiroalkaloid, 7-epi-javaniside (1), was isolated from the Cameroonian plant Pauridiantha callicarpoides, along with seven known compounds viz., javaniside (2), sweroside (3), hymexelsin (4), scopoletin (5), 7,7`-dihydroxy-6,6`-dimethoxy-8,8`-biscoumarin (6), 7,7`-dihydroxy-6,6`- dimethoxy-3,3`-biscoumarin (7), and 4-hydroxy-3-methoxybenzoic acid (8). The structures of the new alkaloid, as well as those of the known compounds, were elucidated by detailed spectroscopic analysis including 1D and 2D NMR and by comparison with the literature data for related compounds.

Graphical Abstract

Spiroalkaloids and Coumarins from the Stem Bark of Pauridiantha callicarpoides

Keywords: Pauridiantha callicarpoides; Rubiaceae; Coumarins; Javaniside; epi-Javaniside; Spiroalkaloids

Received: 2014-2-28

Published Online: 2014-6-2

Published in Print: 2014-6-1

Spiroalkaloids and Coumarins from the Stem Bark of Pauridiantha callicarpoides

Graphical Abstract

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