One-pot Multi-component Synthesis of Mono- and Bis-indolylimidazole Derivatives Using Zn2+@KSF and Their Antibacterial Activity

Nosrat O. Mahmoodi; Iraj Nikokar; Marzieh Farhadi; Atefeh Ghavidast

doi:10.5560/znb.2014-4026

Published by De Gruyter June 2, 2014

One-pot Multi-component Synthesis of Mono- and Bis-indolylimidazole Derivatives Using Zn²⁺@KSF and Their Antibacterial Activity

Nosrat O. Mahmoodi , Iraj Nikokar , Marzieh Farhadi and Atefeh Ghavidast

From the journal Zeitschrift für Naturforschung B

https://doi.org/10.5560/znb.2014-4026

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The preparation of mono- and bis-indolylimidazole derivatives using Zn²⁺ supported on montmorillonite KSF (Zn²⁺@KSF) as an efficient heterogeneous catalyst is described. The structures of these compounds were characterized by IR, ¹H NMR and ¹³C NMR spectroscopy. The antibacterial activity of the selected products was examined. Some products exhibit promising activities.

Graphical Abstract

One-pot Multi-component Synthesis of Mono- and Bis-indolylimidazole Derivatives Using Zn2+@KSF and Their Antibacterial Activity

One-pot Multi-component Synthesis of Mono- and Bis-indolylimidazole Derivatives Using Zn²⁺@KSF and Their Antibacterial Activity

Keywords: Zn2+@KSF; Clay Catalyst; Bis-indole; Indolylimidazole; Multicomponent Reaction (MCR)

Received: 2014-2-2

Published Online: 2014-6-2

Published in Print: 2014-6-1

One-pot Multi-component Synthesis of Mono- and Bis-indolylimidazole Derivatives Using Zn²⁺@KSF and Their Antibacterial Activity

Graphical Abstract

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