This is a page describing data taken during an experiment at the ISIS Neutron and Muon Source. Information about the ISIS Neutron and Muon Source can be found at https://www.isis.stfc.ac.uk.
Interactions of de Novo Designed Antimicrobial Lipopeptides with Model Leaflets of Inner Microbial Membranes – A NR study
Abstract: In this work, we propose to exploit the unique capability of neutron reflection (NR) to study the structural changes of multi-component lipid monolayer models mimicking bacterial membranes upon their exposure to de novo designed ultrashort antimicrobial lipopeptides, focusing on unravelling their unusual mechanism of action. NR is the only technique that can determine the amount and distribution of these represent AMPs once adsorbed. We request 3 days on INTER using the event mode to complete this work.
Public release date: 09 October 2022
Principal Investigator: Professor Jian Lu
Experimenter: Dr Zongyi Li
Experimenter: Dr Lisa Pan
Local Contact: Dr Mario Campana
Experimenter: Mr KE FA
Experimenter: Mr Sean Ruane
Experimenter: Dr Mingrui Liao
Experimenter: Mr Huayang Liu
DOI: 10.5286/ISIS.E.RB1920156-1
Parent DOI: 10.5286/ISIS.E.RB1920156
ISIS Experiment Number: RB1920156
Part Number: 1
Date of Experiment: 04 October 2019
Publisher: STFC ISIS Neutron and Muon Source
Data format: RAW/Nexus
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Data Citation
The recommended format for citing this dataset in a research
publication is as:
[author], [date], [title], [publisher],
[doi]
For Example:
Professor Jian Lu et al; (2019): Interactions of de Novo Designed Antimicrobial Lipopeptides with Model Leaflets of Inner Microbial Membranes – A NR study, STFC ISIS Neutron and Muon Source, https://doi.org/10.5286/ISIS.E.RB1920156-1