D-JRP15–FED-AMR-WP3.3 Deliverable 3.3 Classification of pig farm compartments according to their role in the epidemiology of Clostridioides difficile (task 3.4)
Creators
- 1. Federal Research Institute for Animal Health, Friedrich-Loeffler-Institut, Jena, Germany
- 2. Austrian Agency for Health and Food Safety, Vienna, Austria
- 3. Department Biological Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany
- 4. lnstitute of Technology, University of Tartu, Estonia
- 5. Department of Natural Sciences, National University of Ireland Galway
- 6. Infectious Diseases Department, National Institute of Health DrRicardo Jorge, Lisboa, Portugal
Description
In order to assess C. difficile/AMR dissemination between humans, animals and the environment, studies were conducted on samples from 4 countries (2 HOALs Portugal, Austria, 1 agricultural facility Estonia, single compartments Ireland). The results obtained allowed to perform a classification of pig farm compartments according to their role in the epidemiology of C. difficile, which was identified in all the following ecosystems: pig barn (faeces), manure (pig), wild animals, soil (agricultural fields), river water, ground water, wastewater treatment plant and air. In addition, in each HOAL, a different toxigenic C. difficile RT (RT033, RT078 and RT049, respectively) was dominant, reflecting well-established transmission chains and a resilient source.
Overall, the results obtained from the 3 HOALs/agricultural facility showing the presence of dominant clones in compartments associated with the pig production unit suggest a transmission chain involving these animals. They contribute to unveiling the role played by animal and environmental reservoirs within the C. difficile epidemiology.
Files
D-JRP15–FED-AMR-WP3.3.pdf
Files
(1.2 MB)
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