A complete list of filtered variants and gene lists of frequently and recurrently mutated genes in DLBCL, MCL, T-NHL, and BL, as well as pre-assembled CNV gene list
Creators
- Jakša Radek1
- Karolová Jana2
- Svatoň Michael3
- Kazantsev Dmitry4
- Grajciarová Martina5
- Pokorná Eva4
- Tonar Zbyněk5
- Klánová Magdalena2
- Winkowská Lucie3
- Maláriková Diana2
- Vočková Petra2
- Forsterová Kristina
- Renešová Nicol4
- Dolníková Alexandra4
- Nožičková Kristyna4
- Dundr Pavel1
- Froňková Eva3
- Trněný Marek6
- Klener Pavel2
- 1. Institute of Pathology, University General Hospital Prague and First Faculty of Medicine, Charles University, Prague, Czech Republic
- 2. Institute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague, Czech Republic; First Department of Medicine- Hematology, University General Hospital Prague and First Faculty of Medicine, Charles University, Prague, Czech Republic
- 3. CLIP, Department of Pediatric Hematology/Oncology, Second Faculty of Medicine and University Hospital in Motol, Prague, Czech Republic
- 4. Institute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague, Czech Republic
- 5. Department of Histology and Embryology and Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic
- 6. First Department of Medicine- Hematology, University General Hospital Prague and First Faculty of Medicine, Charles University, Prague, Czech Republic
Description
A complete list of variants which passed filtering described in supplemental methods, that were found in both PDX model sample and patient’s sample from which it was derived (S1A) and variants which were gained (S1B) or lost (S1C) during PDX model derivation. Gene lists for filtration of variants in genes of special interest are included in the table (S1D). Gene list for filtration of CNV changes in genes of special interest is included in the table (S1E). Chr - Chromosome, REF - Reference allele, ALT - Alternative allele, AA change - Amino acid change, Patient AF - Allele frequency in the patient’s sample, Patient Depth – Read depth in patient’s sample, PDX AF- Allele frequency in PDX model sample, PDX Depth - Read depth in PDX sample, DLBCL - Diffuse Large B-cell lymphoma, MCL - Mantle Cell Lymphoma, TCL - T-cell lymphoma, BL – Burkitt Lymphoma, and CNV - Copy Number Variation.
Files
Files
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