Published October 31, 2021
| Version v1
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The microdissected gene expression landscape of nasopharyngeal cancer reveals vulnerabilities in FGF and non-canonical NF-κB signaling.
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Description
Despite extensive mutational profiling, novel therapies targeting the tumor epithelium remain elusive in the majority of patients with nasopharyngeal cancer. Compartment-specific gene expression profiling reveals pathways that are consistently dysregulated in NPC tumors and can serve as useful treatment targets.