Fig. 1 in Identifying SARS-CoV-2related coronaviruses in Malayan pangolins

Fig. 1 | Evolutionary relationships among human SARS-CoV-2,the pangolin coronavirus sequences obtained in this study,and the other reference coronaviruses.(A) Genome organization of coronaviruses including the pangolin coronaviruses,with the predicted ORFs shown in different colors (ORF1a is omitted for clarity).(B) Phylogeny of the subgenus Sarbecovirus (genus Betacoronavirus; n=53) estimated from the concatenated ORF1ab-S-E- M-N genes.Red circles indicate the pangolin coronavirus sequences generated in this study (Extended Data Table 1). Note that GD/P1L is the consensus sequence re-assembled from the raw data previously published7. Phylogenies were estimated using a maximum likelihood approach employing the GTRGAMMA nucleotide substitution model and 1,000 bootstrap replicates.