Association of High-Risk Cervical Human Papillomavirus with Demographic and Clinico- Pathological Features in Asymptomatic and Symptomatic Women

Background Human Papillomavirus (HPV) infection is a common cause of cervical cancer. Based on its oncogenic potential, genotypes with high, low and intermediate risks have been classified. The present study was conducted to detect cervical HPV infection in women with and without symptoms and to study high-risk genotypic distribution of cervical HPV infection among them.Methodology A hospital-based cross-sectional study was conducted from August 2022-September 2023 wherein 81 women in the age group 20-70 years, attending STI/RTI clinic at Government Medical College and Hospital, Nagpur were screened by cervical cytology for cellular changes and histopathology or colposcopy wherever required. RT- PCR was performed to detect high-risk HPV genotypes.This projects a baseline data for treatment, prophylaxis, post vaccination surveillance and future research.

Keywords:- HPV Genotype, RT-PCR, Cytology.