Particle and Cell Cluster Separation Based on Inertial Effects in Rectangular Serpentine Channels

Michal Mulík; Ivan Cimrák

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Paper

Particle and Cell Cluster Separation Based on Inertial Effects in Rectangular Serpentine Channels

Topics: Pattern Recognition, Clustering and Classification; Simulation and Modeling

In Proceedings of the 17th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIOINFORMATICS, 553-560, 2024 , Rome, Italy

Authors: Michal Mulík and Ivan Cimrák

Affiliation: Cell-in-fluid Biomedical Modelling & Computations Group, Faculty of Management Science and Informatics, University of Žilina, Slovakia

Keyword(s): Microfluidics, Inertial Flow, Clusters, PyOIF, ESPResSo, Separation.

Abstract: It is well-established that the inertial effect in microfluidics has a significant impact on particle and cell cluster separation. The outcomes are particularly dependent on the channel geometry and the particle and cell suspensions introduced into the channel. In this study, we investigate various combinations related to the size of a curved channel, fluid velocity, and the size and elasticity of clusters. We quantitatively and qualitatively evaluate the behavior of the examined clusters with respect to separation potential. Computational results suggest specific combinations of flow parameters leading to efficient particle and cell cluster separation.

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Paper citation in several formats:

Mulík, M. and Cimrák, I. (2024). Particle and Cell Cluster Separation Based on Inertial Effects in Rectangular Serpentine Channels. In Proceedings of the 17th International Joint Conference on Biomedical Engineering Systems and Technologies - BIOINFORMATICS; ISBN 978-989-758-688-0; ISSN 2184-4305, SciTePress, pages 553-560. DOI: 10.5220/0012547300003657

@conference{bioinformatics24,
author={Michal Mulík. and Ivan Cimrák.},
title={Particle and Cell Cluster Separation Based on Inertial Effects in Rectangular Serpentine Channels},
booktitle={Proceedings of the 17th International Joint Conference on Biomedical Engineering Systems and Technologies - BIOINFORMATICS},
year={2024},
pages={553-560},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0012547300003657},
isbn={978-989-758-688-0},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the 17th International Joint Conference on Biomedical Engineering Systems and Technologies - BIOINFORMATICS
TI - Particle and Cell Cluster Separation Based on Inertial Effects in Rectangular Serpentine Channels
SN - 978-989-758-688-0
IS - 2184-4305
AU - Mulík, M.
AU - Cimrák, I.
PY - 2024
SP - 553
EP - 560
DO - 10.5220/0012547300003657
PB - SciTePress