KASMEJ
Kastamonu Medical Journal

Kastamonu Medical Journal regularly publishes internationally qualified issues in the field of Medicine in the light of up-to-date information.

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Original Article
Change of critical COVID-19 disease in time
Abstract
Background: COVID-19 disease, which has taken over the world for more than a year, is unfortunately not yet understood and a definitive treatment has not been found. The aim of this study is to investigate the changes in clinical and laboratory tests of critical COVID-19 patients followed in the intensive care unit between March/2020 and December/2020 and to evaluate the factors that cause these changes with literature information. Material and Method: In the study, during the beginning of the pandemic and its progress; 50 COVID-19 patients treated in the intensive care unit between March-April-May/2020 were defined as group 1, and 50 COVID-19 patients treated in the intensive care unit between October-November-December/2020 were defined as group 2. Clinical, laboratory and intensive care processes of the patients in the groups were analyzed retrospectively and compared. Results: Demographic data were similar between groups. Group 2 patients had higher 28-day mortality, and this result was statistically significant (p=0.006). Transfer rates of group 1 patients to the service after intensive care were found to be statistically higher (p=0.029). Conclusion: 28-day mortality was found to be different between similar patient groups who were admitted to intensive care during different periods of the pandemic. The reasons for this may be: changes in pathogenicity as a result of viral mutations, different immune responses of hosts to viral infection, intensive care experience of healthcare professionals.

Keywords : COVID-19, intensive care unit, pandemic, critical patient

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Article available in :
Volume 2, Issue 2, 2022
Page : 35-38
https://doi.org/10.51271/KMJ-0037
Article Information
Received : 03 Şub 2022
Accepted : 20 Mar 2022
Published : 29 Ara 2022
Corresponding Author :

Ufuk Demir: Kastamonu University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Kastamonu, Turkey

[email protected]
Citation : Demir U, Soylu VG, Taşkın Ö, Yılmaz A. Change of critical covid-19 disease in time. Kastamonu Med J. 2022;2(2): 35-38.

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