REVIEW PAPER
Autoimmune/inflammatory syndrome induced by adjuvants – a new diagnostic problem or the solution of a diagnostic riddle
Submission date: 2013-08-26
Final revision date: 2013-10-10
Acceptance date: 2013-10-14
Online publication date: 2013-12-24
Publication date: 2013-12-20
Reumatologia 2013;51(6):437-444
KEYWORDS
TOPICS
ABSTRACT
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) is a newly identified syndrome dealing with pathological effects of adjuvant use. In recent years observations have shown that a number of clinical situations displaying similar features can be associated with an overactive immune response and with the inflammatory effect of adjuvants administration. Chronic stimulation of the immune system by substances used as adjuvants may lead to the occurrence of numerous symptoms such as chronic fatigue, arthritis, myalgia, cognitive impairment and neurological disorders. The aim of this article is to present how and why adjuvants – while allegedly causing no specific immune response – may become a cause of development of autoimmune diseases.
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Copyright: © Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie. This is an Open Access journal, all articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (https://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
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