Twenty-seven cases of cancer patients with bone metastases which resulted in the first manifestation were recognized at the National Cancer Center Hospital of Japan, from March 23rd, 1962 to December 28th, 1965.
Among them 10 cases have primary site in bronchus, unknown in 7 cases, 5 in kidney 3 in prostate, 1 in thyroid, 1 in liver, and remaining 7 cases were not diagnosed their primary site with any of the clinical and cytological examination and autopsy.
4 cases, in which primary lesions were each of bronchus, kidney, prostate and liver, were demonstrated as the very interesting cases with regards to the diagnosis and treatment of the primary lesions and their bone metastases.
Especially, in case of the bone metastasis of cancer of kidney radical nephrectomy was postulated to be performed if possible, despite of the evidence of wide-spread bone metastasis.