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Utilization of Glycine max (Soybean) in Depleting the Platelet Count of Sprague dawley

Volume: 124  ,  Issue: 1 , May    Published Date: 02 May 2023
Publisher Name: IJRP
Views: 188  ,  Download: 167 , Pages: 8 - 13    
DOI: 10.47119/IJRP1001241520234805

Authors

# Author Name
1 Ivan Lexter S. Leaño
2 Angelique C. Baldos
3 Ellen Kate D. Causing
4 Mariel M. Escalderon
5 Diona G. Gutierrez

Abstract

Thrombocytosis in a minimal normal range deviation is not clinically significant but having excessive proliferation and production causes serious complications such as stroke, heart attack, or clot in blood vessels which can be very painful (Cleveland Clinic, 2022). Medication for thrombocytosis associated conditions are available but common drugs are not made for direct platelet reduction. It was recently debuted that at least five years, the side effect of these specific available drugs will outweigh its benefits which is alarming for those who need consistent intake due to gene-linked essential thrombocytosis (Walzer, M., 2019). Philippines, a developing country has a culture of home medication and are after over-the-counter drugs without prescriptions. The societys culture is not proactive in terms of hospitalization and checking up on times of illnesses, but reactive if conditions get worse. In this study, the researcher aimed not to manufacture a pharmaceutical drug, but to appeal to organic consumption to one of abundant iron source food in the country to reduce platelet count which can easily corporate in the diet and lifestyle of Filipinos. Thus, this study utilized 75% Glycine max(soybean) in depleting the platelet count through the diet of Sprague dawley. Platelets are observed in first and second observation with three (3) day interval. The study concluded that effect was only significant in the second observation (6th day) since iron absorption as the main metabolite of interest in Glycine max takes 3 days to be absorbed by Sprague dawley (Huebers, H.A et al., 1990).

Keywords

  • Platelet
  • Sprague dawley
  • Glycine max
  • Depleting platelet count
  • Soybean