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A Special Issue on 5th Annual Meeting of GSZ.
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Vol. VII Issue: 3 (Special Issue)

Abstracts of the 2nd Meeting of the Asian Cellular Therapy Organization
(PACTO 2011)

2011 Vol. 7 (3): p98-148. doi:10.46582/jsrm.0703016 [HTML] [PDF ]
PMCID: PMC3908267  

ORAL PRESENTATION

TRANSPLANTATION 1

(O1) A suitable conditioning regimen in allogeneic hematopoietic stem cell transplantation for adult patients with acute lymphoblastic leukemia

Masahiro Imamura (PACTO 2011-O-001)

JSRM Code: 007030700023

(O2) Haploidentica lFamily Donor for Hematopoietic Transplantation to Treat High Risk Hematological Diseases in Adult

Ming Yao, Shang-Ju Wu, Jih-Luh Tang,Yao-Chang Chen (PACTO 2011-O-002)

JSRM Code: 007030700024

(O3) Hematopoietic stem cell transplantation in China

Kaiyan LIU (PACTO 2011-O-003)

JSRM Code: 007030700025

TRANSPLANTATION 2

(O4) Depletion of Alloreactive T cells for Tolerance Induction in a Recipient of Kidney and Hematopoietic Stem Cell Transplantations

Kanjana Tangnararatchakit, Wiwat Teerapanich, Usanarat Anurathapan, Wiwat Tapaneeyaolarn, Samart Pakakasama, Saengsuree Jootar, Shimon Slavin, Suradej Hongeng (PACTO 2011-O-004)

JSRM Code: 007030700026

(O5) Current Status of Hematopoietic Stem Cell Transplantation (HSCT) in India

Banavali S(PACTO 2011-O-005)

JSRM Code: 007030700027

(O6) Introduction of WHO-WBMT Vietnam Workshop 2011

Yoshihisa Kodera (PACTO 2011-O-006)

JSRM Code: 007030700028

NEW STRATEGY OF TRANSPLANTATION

(O7) Autologous hematopoietic stem cell transplantation in the treatment of severe autoimmune disease

Hiroshi Tsukamoto (PACTO 2011-O-007)

JSRM Code: 007030700029

(O8) The use of Mesenchymal Stromal Cells to modulate Immune Responses: Risk and Benefit

Willem E Fibbe (PACTO 2011-O-008)

JSRM Code: 007030700030

(O9) Nonhomologous Hematopoietic Cell Therapy

Edwin M. Horwitz (PACTO 2011-O-009)

JSRM Code: 007030700031

IMMUNOTHERAPY 1

(O10) New strategy of adoptive-immunotherapy using γ δ T cells

Hirohito Kobayashi(PACTO 2011-O-010)

JSRM Code: 007030700032

(O11) Autologous T cell Therapy Against Tumors

Jaeseung Lim(PACTO 2011-O-011)

JSRM Code: 007030700033

(O12) Ex vivo - expanded allogeneic natural killer cells for clinical application in anti-tumor immunotherapy

Yu-Kyeong Hwang (PACTO 2011-O-012)

JSRM Code: 007030700034

IMMUNOTHERAPY 2

(O13) Dendritic Cell Immunotherapy of Gastrointestinal Tumors

H. Kim Lyerly (PACTO 2011-O-013)

JSRM Code: 007030700035

(O14) Immunotherapy for the Treatment of Advanced Prostate Cancer

Mark W. Frohlich (PACTO 2011-O-014)

JSRM Code: 007030700036

(O15) Clinical translation of Chimeric Antigen Receptor (CAR) messenger RNA (mRNA) loaded T- and NK-cell immunotherapy for safe, tumor-targeted bioactivity

Madhusudan V. Peshwa (PACTO 2011-O-015)

JSRM Code: 007030700037

MESENCHYMAL STEM CELLS

(O16) Systemic MSC Therapy for Genetic and Acquired Orthopedic Disorders

Satoru Otsuru (PACTO 2011-O-016)

JSRM Code: 007030700038

(O17) Mechanisms of MSC (mesenchymal stem cell) accumulation at the sites of tumors

Ryosuke Uchibori, Keiya Ozawa (PACTO 2011-O-017)

JSRM Code: 007030700039

(O18) Oncolytic measles virus-loaded human bone marrow-derived mesenchymal stem cells as systemic cancer therapeutic agents for human hepatocellular carcinoma

Ong HT, Federspiel MJ, Russell SJ,Peng KW and Hui KM (PACTO 2011-O-018)

JSRM Code: 007030700040

GENE THERAPY

(O19) Phase-I trial of T cell-depleted haplo-identical stem cell transplantation (Haplo-SCT) combined with HSV-TK gene modified T cell add-back

Yuji Heike, Takako Wakeda, Takahiro Fukuda, Shinichiro Mori, IkueiNukaya, Jun-ichiMineno, Kazuto Takesako and Yoich Takaue (PACTO 2011-O-019)

JSRM Code: 007030700041

(O20) Engineered T Cell Immunotherapy for Cancer in Japan

Kazuto Takesako (PACTO 2011-O-020)

JSRM Code: 007030700042

(O21) Adoptive T-Cell Therapy for Cancer from the Benchtop to the Bedside and beyond

Renier J Brentjens (PACTO 2011-O-021)

JSRM Code: 007030700043

REGENERATIVE MEDICINE

(O22) Cartilage Repair -Past, Present and Future

Mitsuo Ochi (PACTO 2011-O-022)

JSRM Code: 007030700044

(O23) Strategies for addressing stand-alone corneal epithelial and endothelial diseases using in vitro expanded cells using Nano scaffolds and polymers

Abraham S (PACTO 2011-O-023)

JSRM Code: 007030700045

(O24) Recent advances in clinical application of human stem cells

Kwang-Hoe Chung, Hyung-Min Chung, Dong Ryul Lee, Jisook Moon, Kwang-Yul Cha (PACTO 2011-O-024)

JSRM Code: 007030700046

(O25) Commercialization of allogeneic, off-the-shelf, adult stem cell drug products using human Umbilical Cord Blood-derived Mesenchymal Stem Cells (hUCBMSCs)

Antonio S J Lee (PACTO 2011-O-025)

JSRM Code: 007030700047

(O26) Generation of Functional Platelets from Pluripotent Stem Cells

Hiromitsu Nakauchi (PACTO 2011-O-026)

JSRM Code: 007030700048

FACILITY

(O27) Transition from standard to cGMP manufacturing in a growing laboratory and transplant service

Lawrence S. Lamb (PACTO 2011-O-027)

JSRM Code: 007030700049

(O28) SANYO’S Approach to Aseptic Cell Manufacturing

Sachihiko Kataoka (PACTO 2011-O-028)

JSRM Code: 007030700050

(O29) Development of Automated cell processing system R-CPX for regenerative medicine

Katsumi Nakashima (PACTO 2011-O-029)

JSRM Code: 007030700051

Clinical development in Asia, from CRO point of view

(O30) 1.The current situation of CRO business in Asia
2.Experience of clinical development/study in Asia.
3.Future of clinical development in Asia from CRO point of view

Hidemi Aida(PACTO 2011-O-030)

JSRM Code: 007030700052

REGULATORY SESSION 1

(O31) Stem cell therapy in chronic stroke patients-Phase II trial

Shinn-Zong Lin, Demeral Liu, Woei-Cherng Shyu (PACTO 2011-O-031)

JSRM Code: 007030700053

REGULATORY SESSION 2

(O32) Unproven stem cell treatments: Moving targets on the global landscape

Douglas Sipp (PACTO 2011-O-032)

JSRM Code: 007030700054

REGULATORY SESSION 3

(O33) NK cell therapy for cancer in practice

Jun-ichi Masuyama (PACTO 2011-O-033)

JSRM Code: 007030700055

POSTER PRESENTATION

(P1) Modified donor lymphocyte infusion in the prophylaxis of relapse after HLA-mismatched/haploidentical T-cell-replete hematopoietic stem cell transplantation for advanced-stage acute leukemia: a retrospective risk factors analysis

Wang-Yu, Liu Dai-Hong, Xu Lan-Ping, Liu Kai-Yan, Chen Huan, Zhang Xiao-Hui, Chen Yu-Hong, Han Wei, Huang Xiao-Jun (PACTO 2011-P-034)

JSRM Code: 007030700056

(P2) Modified donor lymphocyte infusion associated acute graft-versus-host disease after haploidentical T-cell-replete hematopoietic stem cell transplantation: incidence and risk factors

Chen-hua Yan, Dai-hong Liu, Lan-ping Xu, Kai-yan Liu, Ting Zhao, Yu Wang, Huan Chen, Yu-hong Chen, Wei Han, Xiao-jun Huang (PACTO 2011-P-035)

JSRM Code: 007030700057

(P3) Lymphoid commitment in human bone marrow CD34-positive cells reflects aging of hematopoietic stem cells.

Yuichi Kodama, Azumi Miyazono, Yasuhiro Okamoto, Yuni Yamaki, Koichiro Kurauchi, Takuro Nishikawa, Takayuki Tanabe, Yuichi Shinkoda, Yoshifumi Kawano (PACTO 2011-P-036)

JSRM Code: 007030700058

(P4) The Study on the Source of Engraftment of Mesenchymal Stem Cells in Patients after Different Source of Hematopoietic Stem Cell Transplantation

Jing Wang, Xiao-Jun Huang, Yu-Hong Chen, Lan-ping Xu, Dai-hong Liu, Huan Chen, Rui-Qin Hou, Xiao-Ying Qin, Kai-yan Liu (PACTO 2011-P-037)

JSRM Code: 007030700059

(P5) Novel natural killer (NK) -cell expansion system for producing large amount (>109 cells) and high purity (>90%) of CD3+ CD56+ cells

Mitsuko Ideno, Mie Yabuuchi, Meiko Jin, Tatsuji Enoki, Naoyuki Sakamoto, Takeshi Ishikawa, Satoshi Kokura, Junichi Mineno (PACTO 2011-P-038)

JSRM Code: 007030700060

(P6) Development of a novel stimulation method to expand CIK cells containing high proportion of CD3+ CD56+ cells

Mitsuko Ideno, Meiko Jin, Tatsuji Enoki, Junichi Mineno (PACTO 2011-P-039)

JSRM Code: 007030700061

(P7) Depletion of CD3-positive cells enables to generate purified and expanded human natural killer cells from peripheral blood mononuclear cells showing strong killer activity

Satoru Saito, Yui Harada, Yoshikazu Yonemitsu (PACTO 2011-P-040)

JSRM Code: 007030700062

(P8) Effect of Herceptin is increased by ex vivo cultured NK cell via antibody-dependent cellular cytotoxicity (ADCC).

Takako Wakeda, Sul Hee Yoon, Yoshinori Ikarashi, Kazunori Aoki, Tsukasa Shinohara, Yuni Yamaki, Yuji Heike (PACTO 2011-P-041)

JSRM Code: 007030700063

(P9) Synergistic anti-cancer effect of large scale simultaneous expanded NK and γ δ T cells with monoclonal antibody drugs

Xuewen Deng, Mie Nieda, Hiroshi Terunuma (PACTO 2011-P-042)

JSRM Code: 007030700064

(P10) Requirements for common chain family cytokines for adoptively transferred γ δ T cell function and homeostasis in vivo

Kazuhiro Kakimi, Takamichi Izumi, Makoto Kondo, Nao Fujieda, Atsushi Kondo, Naohisa Tamura, Ryuji Maekawa, Hirokazu Matsushita (PACTO 2011-P-043)

JSRM Code: 007030700065

(P11) Immune tolerance induction to FVIII in hemophilia A using autologous endothelia progenitors

Hideto Matsui, David Lillicrap, Mitsuhiko Sugimoto, Midori Shima (PACTO 2011-P-044)

JSRM Code: 007030700066

(P12) An Evaluation of CD34+ Cells in the Bone Marrow of various age groups of Indian Population

Abraham S, Manjunath S, Senthilkumar R, Murugan P, Thamaraikannan P, Srinivasan T, Preethy S, Dedeepiya V (PACTO 2011-P-045)

JSRM Code: 007030700067

(P13) Sipuleucel-T: Adaptive Immune Response and Product Characterization from the Phase III IMPACT Trial

Nadeem Sheikh, Daniel Petrylak, Christian Poehlein, James Whitmore, Frances Stewart, Corazon dela Rosa, David Urdal (PACTO 2011-P-046)

JSRM Code: 007030700068

(P14) Cytokine-based log-scale expansion of functional human dendritic cells from PBMC

Yui Harada, Satoru Saito, Yoshikazu Yonemitsu (PACTO 2011-P-047)

JSRM Code: 007030700069

(P15) Efficient antigen presentation by DCs loaded with antigens by electroporation

Koji Nagaoka, Masashi Takahara, Ryuji Maekawa, Takayuki Yoshimoto, Tsuyoshi Teruya, Hiroshi Shiroma (PACTO 2011-P-048)

JSRM Code: 007030700070

(P16) Tissue Factor-triggered Procoagulant Activity of Murine/Human Mesenchymal Stem Cells

Kohei Tatsumi, Kazuo Ohashi, Yoshinori Matsubara, Ayako Kohori, Hiroshi Kakidachi, Akihiro Horii, Takanori Iwata, Teruo Okano (PACTO 2011-P-049)

JSRM Code: 007030700071

(P17) HLA-G Molecules Are Important In Alleviation Of Acute Lung Injury By Placenta Chorion Mesenchymal Stem Cells (pcMSCs) Therapy In Mice Model

Thai-Yen Ling, Meng-Shiue Wu, Yi-Ting Hsieh, Jo-Chi Hsu, Hung-Chih Lai, Fu-Chuo Peng, Jie-Yang Jhuang, Yao-Chang Chen (PACTO 2011-P-050)

JSRM Code: 007030700072

(P18) Useful cell lines (PMDC05/11) of plasmacytoid dendritic cell for cellular immunotherapy

Masuhiro Takahashi, Miwako Narita, Akie Yamahira, Norihiro Watanabe, Shigeo Hashimoto, Yoji Yuki (PACTO 2011-P-051)

JSRM Code: 007030700073

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