Roles of Multidrug Efflux Pumps on the Biofilm Formation of Escherichia coli K-12

KAYO MATSUMURA; SOICHI FURUKAWA; HIROKAZU OGIHARA; YASUSHI MORINAGA

doi:10.4265/bio.16.69

Biocontrol Science

Online ISSN : 1884-0205
Print ISSN : 1342-4815
ISSN-L : 1342-4815

Note

Roles of Multidrug Efflux Pumps on the Biofilm Formation of Escherichia coli K-12

KAYO MATSUMURA, SOICHI FURUKAWA, HIROKAZU OGIHARA, YASUSHI MORINAGA

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Keywords: Biofilm, Escherichia coli, Multidrug efflux pump

JOURNAL FREE ACCESS

2011 Volume 16 Issue 2 Pages 69-72

DOI https://doi.org/10.4265/bio.16.69

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Abstract

We genetically analyzed the roles of multidrug efflux pumps on the biofilm formation of Escherichia coli K-12 BW25113. We used 22 mutants missing various genes related to the multidrug efflux pumps and found that the biofilm formation of emrD, emrE, emrK, acrD, acre and mdtE-deleted mutants was extremely decreased. These results indicate that some multidrug efflux pumps significantly contribute to the biofilm formation of E. coli.

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