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Management of the Knee Problems in Spastic Cerebral Palsy

  • Symposium - Cerebral Palsy
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Abstract

Two common knee problems in cerebral palsy are increased knee flexion during stance phase and reduced knee flexion during the swing phase of gait. We reviewed the recent literature and based on that, we formed this review. Hamstring spasticity, quadriceps weakness, soleus weakness, and lever-arm dysfunction are few factors which lead to increased knee flexion during stance phase. Rectus spasticity diminishes knee flexion in the swing. Resulting gait-stiff knee gait interferes with ground clearance. Both gait patterns result into esthetically poor gait and increased energy consumption. Knee flexion gait may lead to pain in the knee. Natural history of knee flexion gait suggests deterioration over time. In the early stage, these gait abnormalities are managed by nonoperative treatment. Cases in which nonoperative measures fail or advance cases need surgical treatment. Various variables which are taken into consideration before selecting a particular treatment option are described. We also present an algorithm for decision-making. Nonsurgical options and surgical procedures are discussed.

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References

  1. Gage JR. Surgical treatment of knee dysfunction in cerebral palsy. Clin Orthop Relat Res 1990;253:45–54.

    Article  Google Scholar 

  2. Arnold AS, Liu MQ, Schwartz MH, Ounpuu S, Delp SL. The role of estimating muscle-tendon lengths and velocities of the hamstrings in the evaluation and treatment of crouch gait. Gait Posture 2006;23:273–81.

    Article  PubMed  Google Scholar 

  3. Arnold AS, Anderson FC, Pandy MG, Delp SL. Muscular contributions to hip and knee extension during the single limb stance phase of normal gait: A framework for investigating the causes of crouch gait. J Biomech 2005;38:2181–9.

    Article  PubMed  Google Scholar 

  4. Gage JR, Novacheck TF. An update on the treatment of gait problems in cerebral palsy. J Pediatr Orthop B 2001;10:265–74.

    CAS  PubMed  Google Scholar 

  5. Goudriaan M, Nieuwenhuys A, Schless SH, Goemans N, Molenaers G, Desloovere K. A new strength assessment to evaluate the association between muscle weakness and gait pathology in children with cerebral palsy. PLoS One 2018;13:e0191097.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  6. Desailly E, Thévenin-Lemoine C, Khouri N. Does patella lowering improve crouch gait in cerebral palsy? Comparative retrospective study. Orthop Traumatol Surg Res 2017;103:741–6.

    Article  CAS  PubMed  Google Scholar 

  7. Lenhart RL, Brandon SC, Smith CR, Novacheck TF, Schwartz MH, Thelen DG. Influence of patellar position on the knee extensor mechanism in normal and crouched walking. J Biomech 2017;51:1–7.

    Article  PubMed  Google Scholar 

  8. Wiley ME, Damiano DL. Lower-extremity strength profiles in spastic cerebral palsy. Dev Med Child Neurol 1998;40:100–7.

    Article  CAS  PubMed  Google Scholar 

  9. Engsberg JR, Olree KS, Ross SA, Park TS. Spasticity and strength changes as a function of selective dorsal rhizotomy. Neurosurg Focus 1998;4:e4.

    Article  CAS  PubMed  Google Scholar 

  10. Noble JJ, Fry NR, Lewis AP, Keevil SF, Gough M, Shortland AP. Lower limb muscle volumes in bilateral spastic cerebral palsy. Brain Dev 2014;36:294–300.

    Article  PubMed  Google Scholar 

  11. Malavaki CJ, Sakkas GK, Mitrou GI, Kalyva A, Stefanidis I, Myburgh KH, et al. Skeletal muscle atrophy: Disease-induced mechanisms may mask disuse atrophy. J Muscle Res Cell Motil 2015;36:405–21.

    Article  CAS  PubMed  Google Scholar 

  12. Rodda JM, Graham HK, Nattrass GR, Galea MP, Baker R, Wolfe R. Correction of severe crouch gait in patients with spastic diplegia with use of multilevel orthopaedic surgery. J Bone Joint Surg Am 2006;88:2653–64.

    Article  CAS  PubMed  Google Scholar 

  13. Kerr Graham H, Selber P. Musculoskeletal aspects of cerebral palsy. J Bone Joint Surg Br 2003;85:157–66.

    Google Scholar 

  14. Rethlefsen SA, Nguyen DT, Wren TA, Milewski MD, Kay RM. Knee pain and patellofemoral symptoms in patients with cerebral palsy. J Pediatr Orthop 2015;35:519–22.

    Article  PubMed  Google Scholar 

  15. Bell KJ, Ounpuu S, DeLuca PA, Romness MJ. Natural progression of gait in children with cerebral palsy. J Pediatr Orthop 2002;22:677–82.

    PubMed  Google Scholar 

  16. Johnson DC, Damiano DL, Abel MF. The evolution of gait in childhood and adolescent cerebral palsy. J Pediatr Orthop 1997;17:392–6.

    CAS  PubMed  Google Scholar 

  17. Palisano RJ, Cameron D, Rosenbaum PL, Walter SD, Russell D. Stability of the gross motor function classification system. Dev Med Child Neurol 2006;48:424–8.

    Article  PubMed  Google Scholar 

  18. Steele KM, Damiano DL, Eek MN, Unger M, Delp SL. Characteristics associated with improved knee extension after strength training for individuals with cerebral palsy and crouch gait. J Pediatr Rehabil Med 2012;5:99–106.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Novacheck TF, Trost JP, Sohrweide S. Examination of the child with cerebral palsy. Orthop Clin North Am 2010;41:469–88.

    Article  PubMed  Google Scholar 

  20. Katz K, Rosenthal A, Yosipovitch Z. Normal ranges of popliteal angle in children. J Pediatr Orthop 1992;12:229–31.

    Article  CAS  PubMed  Google Scholar 

  21. Boyer ER, Stout JL, Laine JC, Gutknecht SM, Araujo de Oliveira LH, Munger ME, et al. Long term outcomes of distal femoral extension osteotomy and patellar tendon advancement in individuals with cerebral palsy. J Bone Joint Surg Am 2018;100:31–41.

    Article  PubMed  Google Scholar 

  22. Rethlefsen SA, Blumstein G, Kay RM, Dorey F, Wren TA. Prevalence of specific gait abnormalities in children with cerebral palsy revisited: Influence of age, prior surgery, and gross motor function classification system level. Dev Med Child Neurol 2017;59:79–88.

    Article  PubMed  Google Scholar 

  23. Sousa TC, Nazareth A, Rethlefsen SA, Mueske NM, Wren TA, Kay RM. Rectus femoris transfer surgery worsens crouch gait in children with cerebral palsy at GMFCS levels III and I V. J Pediatr Orthop 2017; Apr 3. doi: 10.1097/ BPO.0000000000000988. [Epub ahead of print].

  24. Karol LA, Chambers C, Popejoy D, Birch JG. Nerve palsy after hamstring lengthening in patients with cerebral palsy. J Pediatr Orthop 2008;28:773–6.

    Article  PubMed  Google Scholar 

  25. Young JL, Rodda J, Selber P, Rutz E, Graham HK. Management of the knee in spastic diplegia: What is the dose? Orthop Clin North Am 2010;41:561–77.

    Article  PubMed  Google Scholar 

  26. Thompson NS, Baker RJ, Cosgrove AP, Corry IS, Graham HK. Musculoskeletal modelling in determining the effect of botulinum toxin on the hamstrings of patients with crouch gait. Dev Med Child Neurol 1998;40:622–5.

    Article  CAS  PubMed  Google Scholar 

  27. Corry IS, Cosgrove AP, Duffy CM, Taylor TC, Graham HK. Botulinum toxin A in hamstring spasticity. Gait Posture 1999;10:206–10.

    Article  CAS  PubMed  Google Scholar 

  28. Papadonikolakis AS, Vekris MD, Korompilias AV, Kostas JP, Ristanis SE, Soucacos PN. Botulinum A toxin for treatment of lower limb spasticity in cerebral palsy: Gait analysis in 49 patients. Acta Orthop Scand 2003;74:749–55.

    Article  PubMed  Google Scholar 

  29. Mooney JF 3rd, Koman LA, Smith BP. Pharmacologic management of spasticity in cerebral palsy. J Pediatr Orthop 2003;23:679–86.

    Article  PubMed  Google Scholar 

  30. Bahramizadeh M, Mousavi ME, Rassafiani M, Aminian G, Ebrahimi I, Karimlou M, et al. The effect of floor reaction ankle foot orthosis on postural control in children with spastic cerebral palsy. Prosthet Orthot Int 2012;36:71–6.

    Article  PubMed  Google Scholar 

  31. Rogozinski BM, Davids JR, Davis RB 3rd, Jameson GG, Blackhurst DW. The efficacy of the floor-reaction ankle-foot orthosis in children with cerebral palsy. J Bone Joint Surg Am 2009;91:2440–7.

    Article  PubMed  Google Scholar 

  32. Sung KH, Chung CY, Lee KM, Akhmedov B, Lee SY, Choi IH, et al. Long term outcome of single event multilevel surgery in spastic diplegia with flexed knee gait. Gait Posture 2013;37:536–41.

    Article  PubMed  Google Scholar 

  33. Gordon AB, Baird GO, McMulkin ML, Caskey PM, Ferguson RL. Gait analysis outcomes of percutaneous medial hamstring tenotomies in children with cerebral palsy. J Pediatr Orthop 2008;28:324–9.

    Article  PubMed  Google Scholar 

  34. Nazareth A, Rethlefsen S, Sousa TC, Mueske NM, Wren TA, Kay RM. Percutaneous hamstring lengthening surgery is as effective as open lengthening in children with cerebral palsy. J Pediatr Orthop 2016; Dec 22. doi: 10.1097/BPO.0000000000000924. [Epub ahead of print].

  35. De Mattos C, Patrick Do K, Pierce R, Feng J, Aiona M, Sussman M. Comparison of hamstring transfer with hamstring lengthening in ambulatory children with cerebral palsy: Further followup. J Child Orthop 2014;8:513–20.

    Article  PubMed  PubMed Central  Google Scholar 

  36. Joseph B, Reddy K, Varghese RA, Shah H, Doddabasappa SN. Management of severe crouch gait in children and adolescents with cerebral palsy. J Pediatr Orthop 2010;30:832–9.

    Article  PubMed  Google Scholar 

  37. Moen TC, Dias L, Swaroop VT, Gryfakis N, Kelp-Lenane C. Radical posterior capsulectomy improves sagittal knee motion in crouch gait. Clin Orthop Relat Res 2011;469:1286–90.

    Article  PubMed  Google Scholar 

  38. Rutz E, Gaston MS, Camathias C, Brunner R. Distal femoral osteotomy using the LCP pediatric condylar 90-degree plate in patients with neuromuscular disorders. J Pediatr Orthop 2012;32:295–300.

    Article  PubMed  Google Scholar 

  39. Das SP, Pradhan S, Ganesh S, Sahu PK, Mohanty RN, Das SK. Supracondylar femoral extension osteotomy and patellar tendon advancement in the management of persistent crouch gait in cerebral palsy. Indian J Orthop 2012;46:221–8.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Stout JL, Gage JR, Schwartz MH, Novacheck TF. Distal femoral extension osteotomy and patellar tendon advancement to treat persistent crouch gait in cerebral palsy. J Bone Joint Surg Am 2008;90:2470–84.

    Article  PubMed  Google Scholar 

  41. Novacheck TF, Stout JL, Gage JR, Schwartz MH. Distal femoral extension osteotomy and patellar tendon advancement to treat persistent crouch gait in cerebral palsy. Surgical technique. J Bone Joint Surg Am 2009;91 Suppl 2:271–86.

    Article  PubMed  Google Scholar 

  42. Ganjwala D. Multilevel orthopedic surgery for crouch gait in cerebral palsy: An evaluation using functional mobility and energy cost. Indian J Orthop 2011;45:314–9.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Taylor D, Connor J, Church C, Lennon N, Henley J, Niiler T, et al. The effectiveness of posterior knee capsulotomies and knee extension osteotomies in crouched gait in children with cerebral palsy. J Pediatr Orthop B 2016;25:543–50.

    Article  PubMed  Google Scholar 

  44. Galli M, Cimolin V, Vimercati S, Albertini G, Brunner R. Quantification of patellar tendon shortening in a patient with cerebral palsy. J Appl Biomater Funct Mater 2014;12:57–63.

    PubMed  Google Scholar 

  45. Sossai R, Vavken P, Brunner R, Camathias C, Graham HK, Rutz E. Patellar tendon shortening for flexed knee gait in spastic diplegia. Gait Posture 2015;41:658–65.

    Article  PubMed  Google Scholar 

  46. Al-Aubaidi Z, Lundgaard B, Pedersen NW. Anterior distal femoral hemiepiphysiodesis in the treatment of fixed knee flexion contracture in neuromuscular patients. J Child Orthop 2012;6:313–8.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Klatt J, Stevens PM. Guided growth for fixed knee flexion deformity. J Pediatr Orthop 2008;28:626–31.

    Article  PubMed  Google Scholar 

  48. Bruce WD, Stevens PM. Surgical correction of miserable malalignment syndrome. J Pediatr Orthop 2004;24:392–6.

    Article  PubMed  Google Scholar 

  49. Mosca VS. Calcaneal lengthening for valgus deformity of the hindfoot. Results in children who had severe, symptomatic flatfoot and skewfoot. J Bone Joint Surg Am 1995;77:500–12.

    Article  CAS  PubMed  Google Scholar 

  50. van Vulpen LF, de Groot S, Rameckers E, Becher JG, Dallmeijer AJ. Improved walking capacity and muscle strength after functional power-training in young children with cerebral palsy. Neurorehabil Neural Repair 2017;31:827–41.

    Article  PubMed  Google Scholar 

  51. Mittal S, Farmer JP, Al-Atassi B, Gibis J, Kennedy E, Galli C, et al. Long term functional outcome after selective posterior rhizotomy. J Neurosurg 2002;97:315–25.

    Article  PubMed  Google Scholar 

  52. Adolfsen SE, Ounpuu S, Bell KJ, DeLuca PA. Kinematic and kinetic outcomes after identical multilevel soft tissue surgery in children with cerebral palsy. J Pediatr Orthop 2007;27:658–67.

    Article  PubMed  Google Scholar 

  53. Benner JL, Hilberink SR, Veenis T, Stam HJ, van der Slot WM, Roebroeck ME. Long term deterioration of perceived health and functioning in adults with cerebral palsy. Arch Phys Med Rehabil 2017;98:2196–2050.

    Article  PubMed  Google Scholar 

  54. van den Hecke A, Malghem C, Renders A, Detrembleur C, Palumbo S, Lejeune TM. Mechanical work, energetic cost, and gait efficiency in children with cerebral palsy. J Pediatr Orthop 2007;27:643–7.

    Article  PubMed  Google Scholar 

  55. Cuomo AV, Gamradt SC, Kim CO, Pirpiris M, Gates PE, McCarthy JJ, et al. Health-related quality of life outcomes improve after multilevel surgery in ambulatory children with cerebral palsy. J Pediatr Orthop 2007;27:653–7.

    Article  PubMed  Google Scholar 

  56. Rethlefsen SA, Yasmeh S, Wren TA, Kay RM. Repeat hamstring lengthening for crouch gait in children with cerebral palsy. J Pediatr Orthop 2013;33:501–4.

    Article  PubMed  Google Scholar 

  57. Ma FY, Selber P, Nattrass GR, Harvey AR, Wolfe R, Graham HK. Lengthening and transfer of hamstrings for a flexion deformity of the knee in children with bilateral cerebral palsy: Technique and preliminary results. J Bone Joint Surg Br 2006;88:248–54.

    Article  CAS  PubMed  Google Scholar 

  58. İnan M, Sarikaya İA, Yildirim E, Güven MF. Neurological complications after supracondylar femoral osteotomy in cerebral palsy. J Pediatr Orthop 2015;35:290–5.

    Article  PubMed  Google Scholar 

  59. Böhm H, Hösl M, Döderlein L. Predictors for anterior pelvic tilt following surgical correction of flexed knee gait including patellar tendon shortening in children with cerebral palsy. Gait Posture 2017;54:8–14.

    Article  PubMed  Google Scholar 

  60. Hoffinger SA, Rab GT, Abou-Ghaida H. Hamstrings in cerebral palsy crouch gait. J Pediatr Orthop 1993;13:722–6.

    Article  CAS  PubMed  Google Scholar 

  61. Lee LW, Kerrigan DC, Della Croce U. Dynamic implications of hip flexion contractures. Am J Phys Med Rehabil 1997;76:502–8.

    Article  CAS  PubMed  Google Scholar 

  62. Klotz MC, Hirsch K, Heitzmann D, Maier MW, Hagmann S, Dreher T. Distal femoral extension and shortening osteotomy as a part of multilevel surgery in children with cerebral palsy. World J Pediatr 2017;13:353–9.

    Article  PubMed  Google Scholar 

  63. Shah A, Asirvatham R. Hypertension after surgical release for flexion contractures of the knee. J Bone Joint Surg Br 1994;76:274–7.

    Article  CAS  PubMed  Google Scholar 

  64. Thawrani D, Haumont T, Church C, Holmes L Jr., Dabney KW, Miller F, et al. Rectus femoris transfer improves stiff knee gait in children with spastic cerebral palsy. Clin Orthop Relat Res 2012;470:1303–11.

    Article  PubMed  Google Scholar 

  65. Sutherland DH, Santi M, Abel MF. Treatment of stiff-knee gait in cerebral palsy: A comparison by gait analysis of distal rectus femoris transfer versus proximal rectus release. J Pediatr Orthop 1990;10:433–41.

    Article  CAS  PubMed  Google Scholar 

  66. Marks MC, Alexander J, Sutherland DH, Chambers HG. Clinical utility of the duncan-ely test for rectus femoris dysfunction during the swing phase of gait. Dev Med Child Neurol 2003;45:763–8.

    Article  CAS  PubMed  Google Scholar 

  67. Kay RM, Rethlefsen SA, Kelly JP, Wren TA. Predictive value of the duncan-ely test in distal rectus femoris transfer. J Pediatr Orthop 2004;24:59–62.

    Article  PubMed  Google Scholar 

  68. Ellington MD, Scott AC, Linton J, Sullivan E, Barnes D. Rectus femoris transfer versus rectus intramuscular lengthening for the treatment of stiff knee gait in children with cerebral palsy. J Pediatr Orthop 2018;38:e213–8.

    Article  PubMed  Google Scholar 

  69. Ounpuu S, Muik E, Davis RB 3rd, Gage JR, DeLuca PA. Rectus femoris surgery in children with cerebral palsy. Part II: A comparison between the effect of transfer and release of the distal rectus femoris on knee motion. J Pediatr Orthop 1993;13:331–5.

    Article  CAS  PubMed  Google Scholar 

  70. Muthusamy K, Seidl AJ, Friesen RM, Carollo JJ, Pan Z, Chang FM. Rectus femoris transfer in children with cerebral palsy: Evaluation of transfer site and preoperative indicators. J Pediatr Orthop 2008;28:674–8.

    Article  PubMed  Google Scholar 

  71. Aiona M, Do KP, Feng J, Jabur M. Comparison of rectus femoris transfer surgery done concomitant with hamstring lengthening or delayed in patients with cerebral palsy. J Pediatr Orthop 2017;37:107–10.

    Article  PubMed  Google Scholar 

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Ganjwala, D., Shah, H. Management of the Knee Problems in Spastic Cerebral Palsy. JOIO 53, 53–62 (2019). https://doi.org/10.4103/ortho.IJOrtho_339_17

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