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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2017; 38(04): 535-537
DOI: 10.4103/ijmpo.ijmpo_139_16
Practitioner Section

Primary Leiomyosarcoma of Breast Presenting with Metastasis: An Atypical Presentation with Dismal Prognosis

Garima Singh
Department of Radiotherapy, VMMC and Safdarjung Hospital, New Delhi, India
,
Deepti Sharma
Department of Radiotherapy, VMMC and Safdarjung Hospital, New Delhi, India
,
Surbhi Goyal
Department of Pathology, VMMC and Safdarjung Hospital, New Delhi, India
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Leiomyosarcoma is an extremely uncommon subtype of breast sarcoma, with <50 cases reported in the English literature till date. Patients usually present at an early stage and follow an indolent course. We reported an unusual case of leiomyosarcoma of breast in a post -menopausal female,presented with right side breast lump and pain right side hip. Histomorphological evaluation and immunohistochemistry confirmed the diagnosis. The patient received palliative radiotherapy 20 Gy in 5 fractions to right iliac bone and was started on chemotherapycomprising of docetaxel and epirubicin. Leiomyosarcoma of breast is known to have local recurrence and hematogenous metastasis, usually 10–15 years after the primary diagnosis. Aggressive behavior of leiomyosarcomas in the form of such a rapidly growing, fungating mass of 15 cm in greatest dimension with hematogenous metastasis at the time of initial presentation, as seen in our case, is extremely unusual.

Keywords

Aggressive - breast - leiomyosarcoma - metastasis


Publication History

Article published online:
04 July 2021

© 2017. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used forcommercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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