CC BY-NC-ND 4.0 · Libyan International Medical University Journal 2020; 05(02): 53-58
DOI: 10.4103/LIUJ.LIUJ_8_20
Original Article

Associations between anisometropia and depth of amblyopia in Benghazi, Libya

Sabah Eldressi
Department of Ophthalmology, Benghazi University, Benghazi, Libya
,
Mariam B. Gebril
Department of Ophthalmology, Benghazi University, Benghazi, Libya
› Author Affiliations

Abstract

Background: Amblyopia is a disorder characterized by a decrease in the best-corrected visual acuity in one or both eyes with no clear structural anomalies or ocular pathology. There are three primary types of amblyopia: anisometropic, strabismic, and sensory deprivation amblyopia. Anisometropic amblyopia occurs in children having a difference in refractive error between the two eyes and occurs in the more ametropic eye. Furthermore, there is a strong association of anisometropia with strabismus. Aim: The study aimed to investigate the association between age, sex, laterality, and type of refractive error on the depth of anisometropic amblyopia. Settings and Design: This was a retrospective (observational) study. Data were analyzed using IBM SPSS 23.0 software. Materials and Methods: One hundred and nine patient's files with anisometropic amblyopia were investigated, who were followed in a pediatric eye clinic in Sohail Elatrash's eye hospital Benghazi, Libya, between January 2008 and December 2018. Results: There is no effect of the type of gender on the depth amblyopia with P = 0.57. Furthermore, there is no difference in the predominance of amblyopia between the right and left eye (P = 0.93). Age is correlated in a positive manner with the depth of amblyopia (P = 0.035). Conclusions: in our study, eye laterality and gender had no effect on the depth of anisometropic amblyopia. The age and the smallest amount of astigmatism difference between both eyes had a direct proportion on the depth of anisometropic amblyopia.

Financial support and sponsorship

Nil.




Publication History

Received: 14 April 2020

Accepted: 13 September 2020

Article published online:
14 June 2022

© 2020. Libyan International Medical University. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Von Noorden GK, Campos EC. Binocular vision and ocular motility. In: Theory and Management of Strabismus. 6th ed., CV Mosby, St. Louis; 2001. p. 246 7.
  • 2 Levi DM. Progress and paradigm shifts in spatial vision over the 20 years of ECVP. Perception 1999;28:1443-59.
  • 3 Attebo K, Mitchell P, Cumming R, Smith W, Jolly N, Sparkes R. Prevalence and causes of amblyopia in an adult population. Ophthalmology 1998;105:154-9.
  • 4 Moseley MJ, Fielder AR, Irwin M, Jones HS, Auld RJ. Effectiveness of occlusion therapy in ametropic amblyopia: A pilot study. Br J Ophthalmol 1997;81:956-61.
  • 5 Sjostrand J, Abrahamsson M. Prevention of amblyopia and the concept of cure. Eur J Ophthalmo 1997;l7:121-9.
  • 6 Lai XJ, Alexander J, He M, Yang Z, Suttle C. Visual functions and interocular interactions in anisometropic children with and without amblyopia. Invest Ophthalmol Vis Sci 2011;52:6849-59.
  • 7 Kiorpes L. Visual processing in amblyopia: Animal studies. Strabismus 2006;14:3-10.
  • 8 Kiorpes L, McKee SP. Neural mechanisms underlying amblyopia. Curr Opin Neurobiol 1999;9:480-6.
  • 9 Kiorpes L, Kiper DC, O'Keefe LP, Cavanaugh JR, Movshon JA. Neuronal correlates of amblyopia in the visual cortex of macaque monkeys with experimental strabismus and anisometropia. J Neurosci. 1998;18:6411-24.
  • 10 Friedman DS, Repka MX, Katz J, Giordano L, Ibironke J, Hawse P, et al. Prevalence of amblyopia and strabismus in white and African American children aged 6 through 71 months the Baltimore Pediatric Eye Disease Study. Ophthalmology 2009;116:2128-340.
  • 11 Pai AS, Rose KA, Leone JF, Sharbini S, Burlutsky G, Varma R, et al. Amblyopia prevalence and risk factors in Australian preschool children. Ophthalmology 2012;119:138-44.
  • 12 Pokharel A, Pokharel PK, Das H, Adhikari S. The patternsof refractive errors among the schoolchildren of rural and urban settings in Nepal. Nep J Oph 2010;2:114-20.
  • 13 Williams C. (2009). Amblyopia. BMJ clinical evidence, 2009, 0709.
  • 14 Park KA, Park DY, Oh SY. Analysis of spectral-domain optical coherence tomography measurements in amblyopia: A pilot study. Br J Ophthalmol 2011;95:1700-6.
  • 15 Chua B, Mitchell P. Consequences of amblyopia on education, occupation, and long term vision loss. Br J Ophthalmol 2004;88:1119-21.
  • 16 Lee CE, Lee YC, Lee SY. Factors influencing the prevalence of amblyopia in children with anisometropia. Korean J Ophthalmol 2010;24:225-9.
  • 17 Donahue SP, Arnold RW, Ruben JB; AAPOS Vision Screening Committee. Preschool vision screening: what should we be detecting and how should we report it? Uniform guidelines for reporting results of preschool vision screening studies. J AAPOS 2003;7:314-6.
  • 18 Woodruff G, Hiscox F, Thompson JR, Smith LK. The presentation of children with amblyopia. Eye (Lond) 1994;8 (Pt 6):623-6.
  • 19 Repka M, Simons K, Kraker R; Pediatric Eye Disease Investigator Group. Laterality of amblyopia. Am J Ophthalmol 2010;150:270-4.
  • 20 Latvala ML, Paloheimo M, Karma A. Screening of amblyopic children and long-term follow-up. Acta Ophthalmol Scand 1996;74:488-92.
  • 21 Kutschke PJ, Scott WE, Keech RV. Anisometropic amblyopia. Ophthalmology 1991;98:258-63.
  • 22 Bourne RR, Dineen BP, Ali SM, Noorul Huq DM, Johnson GJ. Prevalence of refractive error in Bangladeshi adults: Results of the National Blindness and Low Vision Survey of Bangladesh. Ophthalmology 2004;111:1150-60.
  • 23 Weale RA. On the age-related prevalence of anisometropia. Ophthalmic Res 2002;34:389-92.