CC BY-NC-ND 4.0 · Asian J Neurosurg 2015; 10(02): 105-107
DOI: 10.4103/1793-5482.145177
CASE REPORT

Langerhans cell histiocytosis in monozygotic twins with central diabetes insipidus and hypophyseal masses

Sung-Tai Wei
1   Department of Neurosurgery, China Medical University and Hospital, Taichung, Taiwan
,
Der-Cherng Chen
1   Department of Neurosurgery, China Medical University and Hospital, Taichung, Taiwan
,
Der-Yang Cho
1   Department of Neurosurgery, China Medical University and Hospital, Taichung, Taiwan
2   Graduate Institute of Immunology, China Medical University, Taichung, Taiwan
,
Hung-Lin Lin
1   Department of Neurosurgery, China Medical University and Hospital, Taichung, Taiwan
› Author Affiliations

Langerhans cell histiocytosis (LCH) is a systemic disease mainly affecting children and young adults. It can manifest as single system disorder or multi-system involvement. When the central nervous system is involved, the hypothalamic-pituitary axis is the most common location affected. Herein we report a rare case of Langerhans cell histiocytosis in monozygotic twins both with central diabetes and hypophyseal masses. This is the first report about LCH in monozygotic twins with hypophyseal lesions.



Publication History

Article published online:
22 September 2022

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