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Egyptian Rheumatology and Rehabilitation
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Detection of serum 25(OH)-vitamin D level in the serum of women with fibromyalgia syndrome and its relation to pain severity

Egyptian Rheumatology and Rehabilitation volume 42, pages 196–200 (2015)Cite this article

Abstract

Objective

The aim of our study is to determine serum 25(OH)-vitamin D level in patients with fibromyalgia syndrome and its relation to pain.

Patients and methods

Fifty-three women with fibromyalgia syndrome diagnosed according to the American College of Rheumatology 1990 fibromyalgia diagnostic criteria and 50 age-matched healthy women as a control group were included in this study. Serum 25(OH)-vitamin D levels were determined in both the patient and the control groups. Fibromyalgia Impact Questionnaire scores and pain intensity measured by the visual analogue scale were evaluated.

Results

We found a statistically significant decrease in serum vitamin D level in the patient group in comparison with the control group. There was a significant negative correlation (P = 0.000) between vitamin D level and Fibromyalgia Impact Questionnaire. The same results are found between vitamin D level and visual analogue scale. There was no significant correlation between vitamin D level and erythrocyte sedimentation rate or C-reactive protein.

Conclusion

We found a significant association between fibromyalgia and low 25(OH)-vitamin D levels as suggested previously in other studies. Also, there was a correlation between the level of vitamin D in serum and severity of pain. We recommend vitamin D screening in every patient with chronic nonspecific musculoskeletal pain, especially fibromyalgia, and extended research in this area with large numbers of patients.

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Authors and Affiliations

  1. Department of Physical Medicine and Rehabilitation, Menoufia University Hospitals, Menoufia University, Menoufia, Egypt

    Alaa A. Elaziz Labeeb PhD & Dina R. Al-Sharaki

Authors
  1. Alaa A. Elaziz Labeeb PhD
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  2. Dina R. Al-Sharaki
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Correspondence to Alaa A. Elaziz Labeeb PhD.

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Elaziz Labeeb, A.A., Al-Sharaki, D.R. Detection of serum 25(OH)-vitamin D level in the serum of women with fibromyalgia syndrome and its relation to pain severity. Egypt Rheumatol Rehabil 42, 196–200 (2015). https://doi.org/10.4103/1110-161X.168202

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  • DOI: https://doi.org/10.4103/1110-161X.168202

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