Early laparoscopic Kasai ’ s procedure in a low weight newborn

successful establishment of postoperative bile flow, the presence of microscopically demonstrable ductal The authors present an early laparoscopic treatment in a newborn with biliary atresia.They describe the structures in the hilum, the degree of parenchyma technical details of the Kasai laparoscopic disease at diagnosis and technical factors of the procedure. A 10-day-old girl, weight 2.4 kg, was anastomosis and diminish of jaundice and hepatic admitted with a history of jaundice and fecal acholia blood-test. Standard operation includes large, painful, since bir th, with elevated total bilirubin and muscle-cutting laparotomy to accomplish hilar abnormal hepatic test. Abdominal ultrasound showed a small gallbladder with hyperechogenicity dissection and porto-enterostomy according to Kasai in porta hepatis and absence of biliary principal duct. technique or variants. [3] In addition children with Other metabolic and hematological tests were biliary atresia are frequently operated upon some normal. The procedure was performed at 20-daydegree of malnutrition and hepatic dysfunction and old by laparoscopy.The cholangiography confirmed they show a high rate of peroperative complications the biliary atresia and Kasai’s procedure was due to surgical trauma. continued by laparoscopy and transumbilical extracorporeal Roux-Y approach. The duration of the procedure was 220 min, with good tolerance of Laparoscopic instrumentation and new techniques pneumoperitoneum due to the laparoscop . have advanced. After first report by Esteves, the Feedings of breast milk began on the third day umbilical approach could be used for safe postoperative, presenting normal colored stools, extracorporeal Roux-en-Y enteric anastomosis in with normalization of the hepatic test. A 20 months follow-up was without complications. babies with laparoscopic assistance. [5] We report that Kasai porto-enterostomy can be performed in a low Biliary atresia, Kasai’s procedure, weight newborn by laparoscopy laparoscopy, newborn complications. The initial result was encouraging and the patient recovered promptly after this procedure. Abstract


INTRODUCTION
Before the introduction of the Kasai porto enterostomy, biliary atresia survival rates were less than 5% at 12 months of age. [1]Survival rates greater than 50% after porto-enterostomy have been reported and with the addition of liver transplantation, survival rates greater than 90% should be now expected. [2]e major determinant factors of a satisfactory outcome following porto-enterostomy are: the patient's age at operation (under three months), the

CASE REPORT
A 10-day-old girl, weight 2.5 kg, was admitted with a history of jaundice, choluria and fecal acholia since birth.The pregnancy had been uneventful and the mother had addiction to morphine.All serologic studies were normal; she was born by normal delivery at 39 weeks' gestation weighing 2.3 kg.Laboratory data by the age of 12 days showed that total bilirubin (Tbil) was 26.4 mg/dl (normal 0.2-1.0);direct bilirubin (Dbil), 12.5 mg/dl; alanine aminotransferase (ALT) 94 IU/l (normal 5-32); aspartate aminotransferase (AST)

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Lopez, et al.: Laparoscopic Kasai's in a newborn 90IU/l (normal 9-32); alkaline phosphatase (AP) 153 IU/l; and gamma-glutamyltransferase (GGT) 180 IU/l (normal 5-35).Other metabolic, hematological and neonatal serologic test results were normal.An ultrasound scan (US) showed a small gallbladder, no intra or extra hepatic bile ducts, with hyperechogenicity at level hepatis portal that suggested the possibility of biliary atresia.At 20 days of age, a laparoscopic exploration was elected.
Treitz ligament and drawn to the umbilical port under direct vision and withdrawn through the umbilicus.The pneumoperitoneum was interrupted to relieve tension on the mesentery as necessary to make extracorporeal transumbilical jejunal Roux-en-Y anastomosis.The jejunum was transected by stapler.Another 40 cm segment beyond the distal was selected for lateral-end anastomosis and was placed back into the abdomen.The correct position of the intestine was checked by laparoscopy.The procedure was performed with the patient positioned at the foot of the table, the surgeon at the patient's feet; the assistant with the camera at the right, the second assistant and instrument nurse at the left.
Anesthesia was performed with inhaled and intravenous agents associated with short acting intravenous opiates and muscle relaxants were administered to facilitate the surgical procedure.The patient was intubated and mechanically ventilated with the inspired oxygen fraction setting at 70%.The examination confirmed a liver cirrhotic appearance an extra hepatic bile-duct atresia by cholangiography with a small, fibrotic gallbladder without passage into biliary duct.For liver exposure we used the palpator in epigastric area which rotates The tied proximal jejunum was passed through the mesocolon and the lateral-end running suture around the porta hepatis was done using intracorporeal self-block sutures posterior and running suture anteriorly [Figure 2].The percutaneus liver biopsy by hepafix needle was associated.upward to expose the porta hepatis (Figure 1).Thereafter, mobilization of the gallbladder following the cystic duct, to the junction with the extra-hepatic duct remnants was performed.The reliquant was divided distally and then dissected toward the hepatic hilum, just to find the division of the portal vein and the hepatic arteries' entry point.This exposition allowed a complete transection of "porta hepatis" just under the liver surface with scissors leaving a surface with ducts draining bile [Figure 1].
With the epigastria trocar the left colon was up forward and the jejunum was secured 20 cm from ) .
Lopez, et al.: Laparoscopic Kasai's in a newborn The tolerance of pneumoperitoneum was acceptable.
The operative time was 220 min.The infant needed no respiratory support postoperatively.Feeding began on the third day, producing normal colored stools on the same day.
Broad-spectrum antibiotics were continued for only three days postoperative and when oral feedings began, amoxicillin and clavulonic was given orally.
The jaundice progressively declined with normalization hepatic function with a follow-up of possible complications related to this approach include: pains, breathing limitation leading to pulmonary complications, nerves damage, prolonged ileus, wound dehiscence, large or recurrent incision hernias, rib damage, peritoneal adhesions.Dehiscence and hernias are usually presented in patients with hypoproteinemia, ascitis, which are common features in these patients. [7]When the procedure was started laparoscopically, its utility was limited only to evaluate the liver status: for irregular liver surface and greenish-brown color in patients with EHBA.The presence or absence of the gallbladder, as well as biliary ducts is obviously atretic by cholangiography.Progressive improvements in instrumentation over the last 15 years have led to Prolonged neonatal jaundice may be caused by the development of 3 mm, short laparoscopic different medical and surgical pathologies.Extra instruments designed specifically for use in the hepatic biliary atresia (EHBA) is one of the causes. [7]ediatric population allowing new techniques and Early diagnosis of EHBA in jaundiced infants is new complex procedures.mandatory, because the success rate of the operation is inversely proportional to the age of the patient, The original technique reported by Esteves showed 80% if the operation is performed when the infant is a new approach for Laparoscopic hilar dissection, younger than 60 days, but the success rate decreases extracorporeal entero-anastomosis and porto 20% if the child is older than three months of age. [8,9]nterostomy with good results.Today this procedure The diagnostic investigations have to be accelerated could decrease theses complications with advantages and the admittance of the patient to the surgical unit of minimally invasive technique, safe, short-lasted, must not be delayed.The evaluation of an infant with the intraabdominal viscera are minimally touched, prolonged jaundice consists of biochemical and the opening is small, [14][15] showing significantly lower serologic tests and abdominal ultrasonography.The incidences of adhesions. [16]Amplified, well-illuminated positive "triangular cord sign" in the abdominal visibility of the tiny hilar structures is guaranteed by ultrasonography is highly suggestive of EHBA, [10] laparoscopy.We believe that laparoscopic porto hepatobiliary scintigraphy and fine-needle liver enterostomy and extracorporeal transumbilical biopsy is carried out. [6,11,12]ejunal anastomosis is a promising technique that may be performed in a low weight newborn without Laparoscopic instrumentation and techniques have complications, allowing the patient to recover 20 months.

DISCUSSION
-advanced to the point that laparoscopic, has found a great spectrum of indications in pediatric surgery and now it is used also in biliary atresia cases. [13]Before the introduction of laparoscopy, laparotomy had to be performed on the infants with prolonged jaundice in whom neonatal hepatitis could not be confirmed with the laboratory, radiology and histopathology investigations.Conventional surgical procedures in biliary atresia, used to gain some bile drainage into the intestine in children; have been achieved through large laparotomy in the upper abdomen.One of the largest incisions in pediatric abdominal surgery, with promptly.The initial results have been encouraging and its real impact will be revealed after additional cases.Theses procedures should be performed by a surgeon experienced both in biliary surgery and advanced laparoscopic to increase the chances for successful results.) .

A 7
mm incision was made in the upper umbilical ring by open technique for the telescope trocar position.The CO² was insufflated to 8 mmHg.Four additional 3.0 mm trocars were placed under direct laparoscopic vision in the left and right upper quadrant, left iliac fossa and epigastric area.

Figure 2
Figure 2: Biliary-digestive anastomosis l i c a t i o n s ( w w w .m e d k n o w .c o m