Vertical lid split approach for optic nerve sheath decompression

We describe a vertical lid split orbitotomy approach to perform optic nerve sheath fenestration which was done in a patient with idiopathic intracranial hypertension. A vertical lid split incision was used to enter the superomedial orbit and approach the optic nerve sheath. This approach resulted in a successful nerve sheath fenestration, with improvement in the patient's symptoms. The vertical lid split incision provides access to the optic nerve sheath with minimal morbidity and may be an option for optic nerve sheath decompression.


Case Report
A 34-year-old overweight woman presented with headache and decreased vision in the left eye over a four-month period. No other risk factors were present for idiopathic intracranial hypertension (IIH). On examination, best-corrected visual acuity was 20/40 in the left eye and 20/20 in the right eye. Color vision was aff ected in the left eye (Ishihara plates, left eye: 7/13, right eye 12/13). A left aff erent pupillary defect was noted. Bilateral papilledema was present, left worse than the right. Humphrey visual Þ elds revealed an enlarged blindspot in the left eye.
Magnetic resonance venography demonstrated dilated retrobulbar optic nerve sheaths, left more than the right. No mass lesions or dural sinus thrombosis was noted. Lumbar puncture showed an elevated opening pressure. Biochemical investigations of the cerebrospinal ß uid (CSF) were normal. A diagnosis of IIH was made and the patient was started on acetozolamide 500 mg twice a day. Ophthalmic review at eight weeks showed mild worsening of visual acuity and color vision in the left eye and early peripheral constriction on the left visual Þ eld.
The patient then underwent a left optic nerve sheath fenestration via a superomedial lid split approach. Under general anesthesia, the left upper lid was inÞ ltrated with local anesthetic with 1:200,000 epinephrine to enhance hemostasis. The medial and superior rectus muscles were secured with 4-0 silk traction sutures to permit globe positioning during surgery. A full-thickness vertical incision was made at the junction of the medial and central thirds of the upper lid. Care was taken to remain exactly perpendicular to the lid margin. Straight iris scissors were used to transect the skin, orbicularis and tarsal plate [ Fig. 1]. The incision was extended superiorly through the levator aponeurosis and palpebral conjunctiva up to the superior fornix. The incision was then extended through the conjunctival fornix continuing down to the bulbar conjunctiva lateral to the plica. Blunt dissection was then used to enter the superomedial orbit. The tendon of the superior oblique was identiÞ ed and retracted medially. The intraconal space was entered between the superior rectus and medial rectus muscles [ Fig. 2]. The globe was retracted laterally to enhance exposure. The optic nerve sheath was identiÞ ed and neurosurgical forceps and scissors were used to open a rectangular window in the dural sheath. Hemostasis was obtained. The bulbar and forniceal conjunctiva were reapproximated with 8-0 polyglactin sutures. The lid incision was repaired in a manner identical to a full-thickness lid margin laceration with 6-0 absorbable polyglactin sutures. The recovery was uncomplicated. Vision in the left eye improved to 20/25; right eye retained 20/20 vision. Visual Þ eld changes resolved and papilledema improved markedly in the left eye. The patient remained on medical management and at the last follow-up at 28 months the Þ ndings were unchanged. Fig. 3 is the postoperative photograph.

Discussion
ONSD is performed to decrease the intra-optic nerve sheath CSF pressure in cases of IIH with visual symptoms. The traditional indication for ONSD is progressive visual symptoms (worsening visual acuity or visual field attributable to papilledema) in the absence of signiÞ cant headache. If headache is prominent then a ventriculo-or lumbo-peritoneal shunt is the procedure of choice. [2] The commonly used approaches for ONSD are the medial transconjunctival approach and the lateral approach, with or without a bone ß ap. [3][4][5] Problems with a medial conjunctival approach include a narrow surgical field, need for disinsertion of the medial rectus and excessive traction on the globe. The lateral approach provides a wider surgical Þ eld but is associated with increased tissue dissection (especially when a bone ß ap is used) and possibility of injury to the ciliary ganglion resulting in pupillary dysfunction. Pelton et al. have described a superomedial lid crease approach to the optic nerve sheath. [6] This approach provides a wide surgical Þ eld but requires retraction of the medial horn of the levator which may result in a temporary medial ptosis. [6] Also, the surgical Þ eld is narrower than that of the lid split approach.
The vertical lid split approach provides good access to the medial intraconal space and is associated with litt le morbidity. In 1962, Byron Smith originally described this technique as a means to gain access to the anterior superomedial orbit. [ Indian Journal of Ophthalmology Vol. 57 No. 4 in which the vertical lid split incision was used to approach the medial intraconal space. [8] The vertical lid split approach provides a wide surgical Þ eld without the need for excessive globe traction or extensive tissue dissection. The incision heals well with no lid dysfunction and good cosmesis. We believe that the vertical lid split approach may be a useful addition to the surgical armamentarium for ONSD.

Raju Bĳ u, Daniel Sushil 1 , Nainan K Georgy 2
Endogenous fungal endophthalmitis is most commonly caused by Candida species and usually occurs in patients with chronic diseases such as diabetes mellitus and renal insufficiency. Voriconazole, a broad-spectrum triazole antifungal agent, att ains therapeutically signiÞ cant concentrations in the vitreous cavity aft er systemic administration. We report, the successful management of presumed endogenous Candida endophthalmitis in a patient with multiple diseases and unstable systemic status with oral voriconazole. Though fungal endophthalmitis has been successfully treated with a combination of intravenous and intravitreal voriconazole, to the best of our knowledge this is the Þ rst report in ophthalmic literature (Medline Search) on the treatment of fungal endophthalmitis with only the oral route of administration of voriconazole.