Download PDF
CC BY-NC-ND 4.0 · Eur J Dent 2015; 09(01): 066-073
DOI: 10.4103/1305-7456.149645
Original Article
Dental Investigation Society

The effect of home-use and in-office bleaching treatments combined with experimental desensitizing agents on enamel and dentin

Karen Pintado-Palomino
1   Department of Dental Materials and Prosthodontics, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
,
Camila Tirapelli
1   Department of Dental Materials and Prosthodontics, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
› Author Affiliations
Further Information

Publication History

Publication Date:
04 September 2019 (online)

  PDF Download Permissions and Reprints

ABSTRACT

Objective: This study aimed to evaluate in vitro the effect of formulations containing Biosilicate to treat enamel and dentin bovine samples exposed to dental bleaching agents. Materials and Methods: On enamel and dentin bleached with commercial gels containing 16% carbamide peroxide (CP) (14 days/4 h) or 35% hydrogen peroxide (single session/45 min), desensitizing dentifrices (Sensodyne®; experimental dentifrice of Biosilicate®; Odontis RX®; Sorriso®) were applied along 14 days and desensitizing pastes (Biosilicate®/water 1:1; Dessensebilize NanoP®; Bioglass type 45S5/water 1:1) were applied on days 1, 3, 7, 10 and 14. Distilled water was the control. Microhardness (MH) and roughness measurements were the variables measured on the samples before and after the treatments. Student's t-test analyzed differences before and after the treatments. Two-way analysis of variance and post-hoc Tukey test analyzed differences among the factors desensitizing, bleaching agents and substrate. Results: Tukey test showed no differences in roughness for both bleaching treatments and among the desensitizing agents (P > 0.05). Differences in MH appeared on enamel treated with in-home bleaching when control group (lower values) was compared with Sensodyne, Biosilicate dentifrice, Biosilicate paste, and Bioglass paste (higher values). Comparisons between desensitizing agents on dentin treated with both bleaching gels showed no statistical differences. Conclusions: The effect of formulations containing Biosilicate (Biosilicate dentifrice and paste) was significant in the MH of enamel bleached with 16% CP.

Key words:

Biomaterial - carbamide peroxide - dental bleaching - hydrogen peroxide
 

  • REFERENCES

  • 1 Dahl JE, Pallesen U. Tooth bleaching – A critical review of the biological aspects. Crit Rev Oral Biol Med 2003; 14: 292-304
    CrossrefPubMedGoogle Scholar
  • 2 Tredwin CJ, Naik S, Lewis NJ, Scully C. Hydrogen peroxide tooth-whitening (bleaching) products: Review of adverse effects and safety issues. Br Dent J 2006; 200: 371-6
    CrossrefPubMedGoogle Scholar
  • 3 Kihn PW. Vital tooth whitening. Dent Clin North Am 2007; 51: 319-31 viii
    CrossrefPubMedGoogle Scholar
  • 4 Goldberg M, Grootveld M, Lynch E. Undesirable and adverse effects of tooth-whitening products: A review. Clin Oral Investig 2010; 14: 1-10
    CrossrefPubMedGoogle Scholar
  • 5 FDI World Dental Federation. FDI policy statement on dental bleaching materials: Adopted by the FDI General Assembly: 17 September 2011-Mexico City, Mexico. Int Dent J 2013; 63: 2-3
    CrossrefPubMedGoogle Scholar
  • 6 Basting RT, Amaral FL, França FM, Flório FM. Clinical comparative study of the effectiveness of and tooth sensitivity to 10% and 20% carbamide peroxide home-use and 35% and 38% hydrogen peroxide in-office bleaching materials containing desensitizing agents. Oper Dent 2012; 37: 464-73
    CrossrefPubMedGoogle Scholar
  • 7 Özcan M, Abdin S, Sipahi C. Bleaching induced tooth sensitivity: Do the existing enamel craze lines increase sensitivity? A clinical study. Odontology 2014; 102: 197-202
    CrossrefPubMedGoogle Scholar
  • 8 Zantner C, Beheim-Schwarzbach N, Neumann K, Kielbassa AM. Surface microhardness of enamel after different home bleaching procedures. Dent Mater 2007; 23: 243-50
    CrossrefPubMedGoogle Scholar
  • 9 Borges AB, Samezima LY, Fonseca LP, Yui KC, Borges AL, Torres CR. Influence of potentially remineralizing agents on bleached enamel microhardness. Oper Dent 2009; 34: 593-7
    CrossrefPubMedGoogle Scholar
  • 10 Borges AB, Yui KC, D'Avila TC, Takahashi CL, Torres CR, Borges AL. Influence of remineralizing gels on bleached enamel microhardness in different time intervals. Oper Dent 2010; 35: 180-6
    CrossrefPubMedGoogle Scholar
  • 11 Zanet CG, Fava M, Alves LA. In vitro evaluation of the microhardness of bovine enamel exposed to acid solutions after bleaching. Braz Oral Res 2011; 25: 562-7
    CrossrefPubMedGoogle Scholar
  • 12 Markovic L, Jordan RA, Lakota N, Gaengler P. Micromorphology of enamel surface after vital tooth bleaching. J Endod 2007; 33: 607-10
    CrossrefPubMedGoogle Scholar
  • 13 Faraoni-Romano JJ, Da Silveira AG, Turssi CP, Serra MC. Bleaching agents with varying concentrations of carbamide and/or hydrogen peroxides: Effect on dental microhardness and roughness. J Esthet Restor Dent 2008; 20: 395-402
    CrossrefPubMedGoogle Scholar
  • 14 Azrak B, Callaway A, Kurth P, Willershausen B. Influence of bleaching agents on surface roughness of sound or eroded dental enamel specimens. J Esthet Restor Dent 2010; 22: 391-9
    CrossrefPubMedGoogle Scholar
  • 15 Sa Y, Sun L, Wang Z, Ma X, Liang S, Xing W. et al. Effects of two in-office bleaching agents with different pH on the structure of human enamel: An in situ and in vitro study. Oper Dent 2012; 38: 100-10
    PubMedGoogle Scholar
  • 16 Gladwell J, Simmons D, Wright JT. Remineralization potential of a fluoridated carbamide peroxide whitening gel. J Esthet Restor Dent 2006; 18: 206-12
    CrossrefPubMedGoogle Scholar
  • 17 Tay LY, Kose C, Loguercio AD, Reis A. Assessing the effect of a desensitizing agent used before in-office tooth bleaching. J Am Dent Assoc 2009; 140: 1245-51
    CrossrefPubMedGoogle Scholar
  • 18 Markowitz K. Pretty painful: Why does tooth bleaching hurt?. Med Hypotheses 2010; 74: 835-40
    CrossrefPubMedGoogle Scholar
  • 19 Pinheiro H, Lopes B, Klautau EB, Cardoso J, Silva BR, Cardoso PE. Influence of bioactive materials used on the dentin surface whitened with carbamide peroxide 16%. Mat Res 2010; 13: 273-8
    CrossrefGoogle Scholar
  • 20 Gjorgievska E, Nicholson JW. Prevention of enamel demineralization after tooth bleaching by bioactive glass incorporated into toothpaste. Aust Dent J 2011; 56: 193-200
    CrossrefPubMedGoogle Scholar
  • 21 Reis A, Tay LY, Herrera DR, Kossatz S, Loguercio AD. Clinical effects of prolonged application time of an in-office bleaching gel. Oper Dent 2011; 36: 590-6
    CrossrefPubMedGoogle Scholar
  • 22 Bonafé E, Loguercio AD, Reis A, Kossatz S. Effectiveness of a desensitizing agent before in-office tooth bleaching in restored teeth. Clin Oral Investig 2014; 18: 839-45
    CrossrefPubMedGoogle Scholar
  • 23 Siqueira RL, Zanotto ED. Biosilicate®: historical of a highly bioactive Brazilian glass-ceramic. Quim Nova 2011; 34: 1231-41
    CrossrefGoogle Scholar
  • 24 Renno AC, Bossini PS, Crovace MC, Rodrigues AC, Zanotto ED, Parizotto NA. Characterization and in vivo biological performance of biosilicate. Biomed Res Int 2013; 2013: 141427
    PubMedGoogle Scholar
  • 25 Hench LL. The story of Bioglass. J Mater Sci Mater Med 2006; 17: 967-78
    CrossrefPubMedGoogle Scholar
  • 26 Kokubo T, Kim HM, Kawashita M. Novel bioactive materials with different mechanical properties. Biomaterials 2003; 24: 2161-75
    CrossrefPubMedGoogle Scholar
  • 27 Tirapelli C, Panzeri H, Soares RG, Peitl O, Zanotto ED. A novel bioactive glass-ceramic for treating dentin hypersensitivity. Braz Oral Res 2010; 24: 381-7
    CrossrefPubMedGoogle Scholar
  • 28 Cunha AG, De Vasconcelos AA, Borges BC, Vitoriano JdeO, Alves-Junior C, Machado CT. et al. Efficacy of in-office bleaching techniques combined with the application of a casein phosphopeptide-amorphous calcium phosphate paste at different moments and its influence on enamel surface properties. Microsc Res Tech 2012; 75: 1019-25
    CrossrefPubMedGoogle Scholar
  • 29 De Abreu DR, Sasaki RT, Amaral FL, Flório FM, Basting RT. Effect of home-use and in-office bleaching agents containing hydrogen peroxide associated with amorphus calcium phosphate on enamel microhardness and surface roughness. J Esthet Restor Dent 2011; 23: 158-68
    CrossrefPubMedGoogle Scholar
  • 30 Moura J, Teixeira LN, Ravagnani C, Peitl O, Zanotto ED, Beloti MM. et al. In vitro osteogenesis on a highly bioactive glass-ceramic (Biosilicate). J Biomed Mater Res A 2007; 82: 545-57
    PubMedGoogle Scholar
  • 31 Roriz VM, Rosa AL, Peitl O, Zanotto ED, Panzeri H, de Oliveira PT. Efficacy of a bioactive glass-ceramic (Biosilicate) in the maintenance of alveolar ridges and in osseointegration of titanium implants. Clin Oral Implants Res 2010; 21: 148-55
    CrossrefPubMedGoogle Scholar
  • 32 Tirapelli C, Panzeri H, Lara EH, Soares RG, Peitl O, Zanotto ED. The effect of a novel crystallised bioactive glass-ceramic powder on dentine hypersensitivity: A long-term clinical study. J Oral Rehabil 2011; 38: 253-62
    CrossrefPubMedGoogle Scholar
  • 33 Cakir FY, Korkmaz Y, Firat E, Oztas SS, Gurgan S. Chemical analysis of enamel and dentin following the application of three different at-home bleaching systems. Oper Dent 2011; 36: 529-36
    CrossrefPubMedGoogle Scholar
  • 34 Browning WD, Cho SD, Deschepper EJ. Effect of a nano-hydroxyapatite paste on bleaching-related tooth sensitivity. J Esthet Restor Dent 2012; 24: 268-76
    CrossrefPubMedGoogle Scholar
  • 35 Reis A, Kossatz S, Martins GC, Loguercio AD. Efficacy of and effect on tooth sensitivity of in-office bleaching gel concentrations: A randomized clinical trial. Oper Dent 2013; 38: 386-93
    CrossrefPubMedGoogle Scholar
  • 36 Dominguez JA, Bittencourt B, Michel M, Sabino N, Gomes JC, Gomes OM. Ultrastructural evaluation of enamel after dental bleaching associated with fluoride. Microsc Res Tech 2012; 75: 1093-8
    CrossrefPubMedGoogle Scholar
  • 37 Klaric E, Marcius M, Ristic M, Sever I, Prskalo K, Tarle Z. Surface changes of enamel and dentin after two different bleaching procedures. Acta Clin Croat 2013; 52: 419-29
    PubMedGoogle Scholar
  • 38 Joiner A. Review of the effects of peroxide on enamel and dentine properties. J Dent 2007; 35: 889-96
    CrossrefPubMedGoogle Scholar
  • 39 Abouassi T, Wolkewitz M, Hahn P. Effect of carbamide peroxide and hydrogen peroxide on enamel surface: An in vitro study. Clin Oral Investig 2011; 15: 673-80
    CrossrefPubMedGoogle Scholar
  • 40 Pedreira De FreitasAC, Botta SB, Teixeira FdeS, Salvadori MC, Garone-Netto N. Effects of fluoride or nanohydroxiapatite on roughness and gloss of bleached teeth. Microsc Res Tech 2011; 74: 1069-75
    CrossrefPubMedGoogle Scholar
  • 41 Featherstone JD, ten Cate JM, Shariati M, Arends J. Comparison of artificial caries-like lesions by quantitative microradiography and microhardness profiles. Caries Res 1983; 17: 385-91
    CrossrefPubMedGoogle Scholar
  • 42 Rodrígues JA, Basting RT, Serra MC, Rodrígues JúniorAL. Effects of 10% carbamide peroxide bleaching materials on enamel microhardness. Am J Dent 2001; 14: 67-71
    PubMedGoogle Scholar
  • 43 Wefel JS. Root caries histopathology and chemistry. Am J Dent 1994; 7: 261-5
    PubMedGoogle Scholar