1 |
Naekwa (Internal Medicine) |
2006 |
A study on using streptomycin with Lanthanide (le-mycing) for PTB |
PTB |
Adults |
Trt 132 |
INH 500 mg QD for 6 mo+SM with lanthanide (le-mycing) IM QD for 1 mo, then IM QOD for 2 mo |
INH 500 mg QD for 6 mo+SM 1,000,000 U IM QD for 1 mo then IM QOD for 2 mo |
Microbiologic, radiographic improvement, adverse events at 6 mo |
Cont 27 |
2 |
Naekwa (Internal Medicine) |
2006 |
Treatment of chronic invasive PTB with intralesional injection of mixed solution of INH/RIF/tuberculin |
PTB |
Adults |
Trt 40 |
INH 500 mg+RIF 500 mg PO QD+SM 1 g IM QD for 4 mo+INH 500 mg/RIF 500 mg QOD for 2 mo+INH/RIF mixed solution 6 mL+tuberculin diluent 0.1 mL percutaneous intralesional injection BIW for 3 mo |
INH 500 mg+RIF 500 mg PO QD+SM 1 g IM QD for 4 mo+INH 500 mg/RIF 500 mg QOD for 2 mo+INH/RIF mixed solution 6 mL percutaneous intralesional injection twice a week |
Microbiologic, clinical improvement, radiographic improvement |
Cont 35 |
3 |
Naekwa (Internal Medicine) |
2006 |
Clinical study for the treatment of tuberculous exudative meningitis with DC magnetic field and anti-TB drug |
TB pleurisy |
Adults |
Trt 50 |
INH+SM+thoracentesis+DC magnetic field therapy for 20 min, not specified further for the treatment |
INH+SM+thoracentesis, not specified further for the treatment |
Subjective symptom (fever, dyspnea, chest pain etc.), body temperature, ESR in peripheral blood, pleural adhesion |
Cont 50 |
4 |
Naekwa (Internal Medicine) |
2006 |
Treatment of epididymal tuberculosis with a combination of snake venom and anti-TB chemotherapy |
TB epididymitis |
Adults |
Trt 80 |
0.0005% Snakes venom 1.0 mL local injection BIW or TIW+DOTS III, not specified further for the treatment |
DOTS III category, not specified further for the treatment |
Subjective symptoms (pain, tenderness), size of induration, volume of semen |
Cont 40 |
5 |
Naekwa (Internal Medicine) |
2007 |
Treatment of PTB with intralesional injection of mixed solution of snake venom and INH/RIF |
PTB |
Children |
Trt 50 |
Added mixed solution of 3 mL of INH (250 mg)/RIF (150 mg) and 2 mL 0.005% snake venom percutaneous intralesional injection BIW for 6 mo |
INH 500 mg QD/RIF 500 mg PO QD/SM 1,000,000 U IM QD for 2 mo+INH 500 mg QD/RIF 500 mg QD/PZA 1,500 mg QOD for 2 mo+INH 500 mg QOD/RIF 500 mg QOD/KM 1,000,000 U IM QOD |
Microbiologic, radiographic improvement |
Cont 25 |
6 |
Soa, sanbuinkwa (Pediatrics, OBGYN, Surgery) |
2007 |
TB drug inhalation and magnet application for pediatric PTB |
PTB |
Children |
Trt 50 |
INH and RIF inhalation treatment and magnet application to the chest for 1 hour QD, no detailed information |
INH and RIF inhalation treatment, no detailed information |
Radiographic improvement, change of ESR and lymphocyte count in peripheral blood |
Cont 35 |
7 |
Soa, sanbuinkwa (Pediatrics, OBGYN, Surgery) |
2007 |
CSF drainage and intrathecal injection of anti-TB drug for the treatment of pediatric TBM |
TBM |
Children |
Trt 30 |
CSF drainage and intrathecal injection of mixed solution of INH/RIF/hydrocortisone QD or QOD or QW |
Anti-TB medication no detailed information |
Subjective symptoms (fever, pain, weakness, etc.), meningeal symptoms, CSF profile, CT change |
Cont 49 |
8 |
Soa, sanbuinkwa (Pediatrics, OBGYN, Surgery) |
2010 |
CSF drainage and intrathecal injection of mixed solution of RIF/hydrocortisone for the treatment of pediatric TBM |
TBM |
Children |
Trt 60 |
CSF drainage and intrathecal injection of mixed solution of RIF/hydrocortisone TIW+DOTS, no detailed information |
DOTS, no detailed information |
Subjective symptoms (fever, pain, weakness, etc.), meningeal symptoms, CSF profile |
Cont 70 |
9 |
Chosŏn ŭihak (Chosun Medicine) |
2014 |
Treatment of exudative pleurisy with combination of Hojangngu and anti- TB drugs |
TB pleurisy |
Not specified |
Trt 15 |
Hojanggun (60 g)+INH 500 mg+mycing 1,000,000 U IM for 1 mo |
INH 500 mg+mycing 10,000,000 U IM for 1 mo |
Subjective symptom (fever, dyspnea, chest pain, etc.), radiographic improvement |
Cont 12 |
10 |
Naekwa (Internal Medicine) |
2015 |
Treatment of mesenteric TB lymphadenitis with laparoscopic ultraviolet irradiation |
TB lymphadenitis |
Not specified |
Trt 12 |
laparoscopic UV radiation for 2 min+INH+RIF 450 mg+SM 1,000,000 IU IM for 3 mo |
INH+RIF 450 mg+SM 1,000,000 IU IM for 3 mo |
Subjective symptom (fever, abdominal pain, abnormal bowel sound, etc.), ESR in peripheral blood, ultrasonic improvement for LN |
Cont 9 |
11 |
Naekwa (Internal Medicine) |
2015 |
Clinical study for the treatment of TBM by intrathecal injection |
TBM |
Not specified |
Trt 12 |
Intrathecal injection of mixed solution of isotubo 3-4 mL, dexamethasone 0.5-1.0 mL, and 0.2% levofloxacin 2 mL QD for 5-7 days; then, QW or BIW for 2-3 mo+anti-TB medication QOD; duration not specified |
Anti-TB medication every other day no detailed information |
Subjective symptoms (fever, headache, vomiting, etc.), degree of meningeal irritation sign, ESR in blood, CSF profile |
Cont 9 |
12 |
Yebang ŭihak (Preventive medicine) |
2016 |
Treatment of TBM by CSF exchange and intrathecal injection |
TBM |
Adults and children |
Trt 29 |
Combination of INH/RIF/EMB/PZA/SM+exchange of CSF/saline and intrathecal injection of mixed solution of INH/RIF/hydrocortisone 25 mg QD or QOD; duration not specified |
DOTS, no detailed information |
CSF profile |
Cont 20 |
13 |
Koryo ŭihak (Korea Medicine) |
2016 |
Treatment of pediatric TB lymphadenitis with haneultali neosam tablet |
TB lymphadenitis |
Children |
Trt 53 |
INH 5 mg/kg/RIF 10 mg/kg/haneultali neosam tablet 500-1,000 mg TID for 2 mo+INH/RIF TIW/haneultali neosam tablet 500 mg TID for 4 mo |
INH/RIF/EMB/PZA for 2 mo+INH 10 mg/kg/RIF 10 mg/kg for 4 mo |
Subjective symptoms (sweating, size of lymph node, ESR in peripheral blood, AFB smear of lymph node aspirate) |
Cont 43 |
14 |
Yebang ŭihak (Preventive medicine) |
2018 |
Treatment of TBM sequelae with sacral epidural injection |
TBM |
Adults |
Trt 19 |
Epidural injection of hydrocortisone 30 mg/5% vitamin B 4.0 mL/vitamin B12 1,000 r 1.0 mL+saline 10.0 mL Q3D, 5 times at sacral level |
Hydrocortisone 30 mg/vitamin B 4.0 mL/saline 500 mL intravenous injection+vitamin B12 1000 r 1.0 mL IM injection Q3D for 1 mo |
Subjective symptoms (pain, weakness), degree of peripheral paralysis, functional disability scale |
Cont 10 |
15 |
Yebang ŭihak (Preventive Medicine) |
2018 |
Treatment of TBM with combination of milk vetch root drug and anti-TB drugs |
TBM |
Adults |
Trt 16 |
INH/RIF/SM QD+milk vetch root drug 2 mL IM QD; duration not specified |
INH/RIF/SM QD; duration not specified |
Body temperature, meningeal symptoms, ESR in peripheral blood |
Cont 14 |