Bioactive Composite Materials for Bone Tissue Applications

B.J.M. Leite Ferreira; M.G.G.M. Duarte; M. Helena Gil; Rui N. Correia; J. Román; Maria Vallet-Regí

doi:10.4028/www.scientific.net/MSF.514-516.985

Paper Titles

Formation of Bone-Like Apatite on Polymeric Surfaces Modified with -SO₃H Groups
p.966

Biomorphic Silicon Carbide Ceramics Coated with Bioactive Glass for Medical Applications
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Scale-up of Poly[(Vinyl Chloride)-b-(n-Butyl Acrylate)-b-(Vinyl Chloride)] prepared by Living Radical Polymerization
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Bone Tissue Engineering Constructs Based on Starch Scaffolds and Bone Marrow Cells Cultured in a Flow Perfusion Bioreactor
p.980

Bioactive Composite Materials for Bone Tissue Applications
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Study of the Fosfosal Controlled Permeation through Glutaraldehyde Crosslinked Chitosan Membranes
p.990

Enzymatic Degradation Behaviour of Starch Conjugated Phosphorylated Chitosan
p.995

Physicochemical Characterization of Novel Chitosan-Soy Protein/ TEOS Porous Hybrids for Tissue Engineering Applications
p.1000

Preparation and Characterization of Chitosan-Based Scaffolds for Biomedical Applications
p.1005

HomeMaterials Science ForumMaterials Science Forum Vols. 514-516Bioactive Composite Materials for Bone Tissue...

Bioactive Composite Materials for Bone Tissue Applications

Abstract:

Two materials with potential application in bone tissue repair have been developed: 1) a non-biodegradable composite based in a new methacrylic-co-acrylic matrix; and 2) a biodegradable composite based in a chitosan (Ch) matrix. Both matrices were reinforced with glass-ceramic particles of composition (mol%) 70 SiO2 – 30 CaO. The in vitro bioactivity of composites was assessed by soaking in simulated body fluid (SBF) for periods of up to 7 days at 37º C. X-ray diffraction (XRD) and scanning electron microscopy coupled with X-ray energy dispersive spectroscopy (SEM-EDS) were used for deposit identification after different soaking periods. Calcium phosphate particulate deposits were detected after 3 days of immersion, followed by growth and maturation towards apatite.

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Periodical:

Materials Science Forum (Volumes 514-516)

Pages:

985-989

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.514-516.985

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Online since:

May 2006

Authors:

B.J.M. Leite Ferreira, M.G.G.M. Duarte, M. Helena Gil, Rui N. Correia, J. Román, Maria Vallet-Regí

Keywords:

Bioactivity, Chitosan (CS), Composite, Glas Ceramics, In Vitro, Poly(methyl methacrylate) (PMMA), Scaffold, Surface Layer

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References

[1] Yoshifumi Okada, Keiichi Kawanabe, Hiroshi Fujita, Ken Nishio, takashi Nakamura: J. Biomed. Mater. Res. Vol. 47 (1999), p.353.

Google Scholar

[2] D.T. Beruto, S.A. Mezzasalma, M. Capurro, R. Botter, P. Cirillo: J. Biomed. Mater. Res. Vol. 49 (2000), p.498.

Google Scholar

[3] Weam F. Mousa, Masahiko Kobayashi, Shuichi Shinzato, Masaki Kamimura, Masashi Neo, Satoru Yoshihara, Takashi Nakamura: Biomaterials Vol. 21, (2000), p.2137.

DOI: 10.1016/s0142-9612(00)00097-1

Google Scholar

[4] M. Vallet-Regí, A.M. Romero, C.V. Ragel, R.Z. Legeros: J. Biomed. Mater. Res. Vol. 44, (1999), p.416.

Google Scholar

[5] B. J. M. Leite Ferreira, M. G. G. M. Duarte, M. H. Gil, R. N. Correia, J. Román and M. ValletRegí, BioÉvora, Key Enginnering Materials Vols. 254-256 (2004), p.581.

Google Scholar

[6] X-ray powder data file, ASTM 74-0874.

Google Scholar

[7] X-ray powder data file, ASTM 09-0432.

Google Scholar

[8] M. N. Khalid, F. Agnely, N. Yagoubi, J. L. Grossiord, G. Couarraze, European Journal of Pharmaceutical Sciences Vol. 15, (2002), p.425.

DOI: 10.1016/s0928-0987(02)00029-5

Google Scholar

[9] A. Chenite, C. Chaput, D. Wang, C. Combes, M. D. Buschmann, C. D. Hoemann, J. C. Leroux, B. L. Atkinson, F. Binette, A. Selmani, Biomaterials Vol. 21, (2000), p.2155.

DOI: 10.1016/s0142-9612(00)00116-2

Google Scholar

[10] Zhao, Jiang Chang, J. of Mat. Sci.: Mat. in Med. Vol. 15, (2004), p.625.

Google Scholar

[11] Zhang Li, Li Yubao, Yang Aiping, Peng Xuelin, Wang Xuejiang, Zhang Xiang, J. of Mat. Sci.: Mat. in Med. Vol. 16, (2005), p.213.

Google Scholar