The Effect of Black Cumin (Nigella sativa sp.) Gel Extract in Wound Healing Process Post Tooth Extraction

Rahmi Syaflida Dalimunte; Olivia Avriyanti Hanafiah; Hendry Rusdy

doi:10.4028/www.scientific.net/JBBBE.48.41

Paper Titles

Retreatment and Restoration Using Individual Formable Fibre Post and Crown - Case Report
p.15

Root Canal Treatment and Endodontic Surgery on Maxillary Incisor with Radicular Cyst
p.22

Management of Ellis Class III Fracture in Two Maxillary Incisivus
p.29

Endodontic Retreatment and Comprehensive Endo-Prosthetic of Premolars: A Case Report
p.34

The Effect of Black Cumin (Nigella sativa sp.) Gel Extract in Wound Healing Process Post Tooth Extraction
p.41

Early Childhood Caries and its Correlation with Secretory Immunoglobulin A
p.47

Phyto Effect of Punica granatum on the Remodelling of Maxilla Bone, Study of Osteoblast and Osteoclast
p.54

Surface Microstructure Study of Self Cured Acrylic Resin after Immersion in Arabica Gayo Coffee
p.62

Glass Ionomer Cement (GIC) Surface Hardness after Addition of 5% Silica from Sea Sand
p.70

HomeJournal of Biomimetics, Biomaterials and...Journal of Biomimetics, Biomaterials and...The Effect of Black Cumin (Nigella sativa sp.) Gel...

The Effect of Black Cumin (Nigella sativa sp.) Gel Extract in Wound Healing Process Post Tooth Extraction

Abstract:

Objective: This study aims to investigate the effects of black cumin extract (Nigella sativa) on the process of wound healing in tooth extraction sockets. Material and Methods: This study involved 24 patients from the Department of Oral and Maxillofacial Surgery grouped into the control and treatment groups. After extracting the first or second molar left or right in adult patients, the black cumin extractwas applied to the socket in the treatment group as soon as possible while it was not applied in the control group. The sockets were divided into 1,2,3 groups, which were treated as black cumin extracts of 10%, 12%, and 14% respectively. On day 1,3,7, patients were recalled and sockets size were calculated to analyze wound healing. Results: Black cumin was found to be able to make the wound healing faster in the treatment group when compared to the control group. Although the effect was not immediately apparent on the second day, on the seventh day the group treated with black cumin extract had a smaller sizing average compared to the control group. The concentration of 12% black cumin extract was found to have the best effect on wound healing. Significance of findings: Black cumin extract can make wound healing in tooth extraction sockets in patients.

You might also be interested in these eBooks

Journal of Biomimetics, Biomaterials and Biomedical Engineering Vol.48

View Preview

Info:

Periodical:

Journal of Biomimetics, Biomaterials and Biomedical Engineering (Volume 48)

Pages:

41-46

DOI:

https://doi.org/10.4028/www.scientific.net/JBBBE.48.41

Citation:

Cite this paper

Online since:

November 2020

Authors:

Rahmi Syaflida Dalimunte*, Olivia Avriyanti Hanafiah, Hendry Rusdy

Keywords:

Extract, Nigella Sativa, Tooth Extraction, Wound Healing

Export:

RIS, BibTeX

Price:

Permissions:

Request Permissions

* - Corresponding Author

References

[1] Ardiana T, Kusuma ARP, Firdausy MD. Efektivitas pemberian gel binahong (Anredera cordifolia) 5% terhadap jumlah sel fibroblast pada soket pasca pencabutan gigi marmut (Cavia cobaya). Odonto Dent J. 2 (2015) 64–70.

DOI: 10.30659/odj.2.1.64-70

Google Scholar

[2] Oroh CG, Pangemanan DHC, Mintjelungan CN. Efektivitas lendir cekicot (Achatina fulica) terhadap jumlah sel fibroblas pada luka pasca pencabutan gigi tikus Wistar. J E-Gigi. 3(2) (2015) 515–20.

DOI: 10.35790/eg.3.2.2015.10325

Google Scholar

[3] Guo S, DiPietro LA. Critical review in oral biology & medicine: Factors affecting wound healing. J Dent Res. 89(3) (2010) 219–29.

Google Scholar

[4] Raja W, Dewangan T. Determination of antibacterial activity of nigella sativa seed extract against some human pathogenic bacteria. American J of Bio and Pharm Res 3(2) (2016) 65-69.

Google Scholar

[5] Sultana S, Asif HM, Akhtar N, Iqbal A, Nazar H, Rehman RU. Nigella sativa: Monograph. J of Pharmacognosy and Phytochem 4 (4) (2015) 103-6.

Google Scholar

[6] Gonzalez ACO, Andrade ZA, Costa TF, Medrado ARAP. Wound healing – a literature review. An Bras Dermatol. 91 (5) (2016) 614-20.

DOI: 10.1590/abd1806-4841.20164741

Google Scholar

[7] Dharma, B., Prihatiningsih dan Rahardjo, Pengaruh Suplemen Zink terhadap Pembentukan Kolagen pada Soket Gigi Marmut yang Mengalami Defisiensi Zink Pasca Pencabutan Gigi, J Ked Gi, (2010).

DOI: 10.22146/majkedgiind.8743

Google Scholar

[8] Niluh Ringga W. Pemberian salep ekstrak Jinten Hitam (Nigella sativa) terhadap peningkatan kepadatan sabut kolagen pada mukosa oral Marmut (Cavia cobaya).Oral biology dental journal. 4(1) (2012) 30-34.

Google Scholar

[9] Han G, Celley R. Chronic wound healing : a review of current management and treatments. Adv Ther.(2016) 1-12.

Google Scholar

[10] Maya J Morison. Seri pedoman praktis manajemen luka. Ed. Florinda. EGC. Jakarta. (2012) 14-25.

Google Scholar

[11] Kareem JJ. Post operative complications associated with non-surgical tooth extraction. Mustansiria Dent J. 5(1) (2008) 104–13.

DOI: 10.32828/mdj.v5i1.514

Google Scholar