Antibacterial Effects of Sol-Gel Derived Zinc-Containing Hydroxyapatite

Xin Chang Shi; H.Z. Jiang; J. Xue; Yun Mao Liao; L.Y. Xiao; C.Y. Bao; W. Li

doi:10.4028/www.scientific.net/KEM.361-363.139

Paper Titles

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Biocompatibility Evaluation of Porous Si-Containing Hydroxyapatite Derived from Coral
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Qualitative and Quantitative Evaluation of Bone and Synthetic Calcium Phosphates Using Raman Spectroscopy
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Antibacterial Effects of Sol-Gel Derived Zinc-Containing Hydroxyapatite
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Fast and Simultaneous Determination of Calcium and Phosphorous in Calcium Phosphate Based Bioceramics by ICP-AES
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Microstructural Observation of Calcium-Deficient Single Crystal Apatite Fibers and Phase Changes during Heating
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HomeKey Engineering MaterialsKey Engineering Materials Vols. 361-363Antibacterial Effects of Sol-Gel Derived...

Antibacterial Effects of Sol-Gel Derived Zinc-Containing Hydroxyapatite

Abstract:

In order to modify the biological properties of pure hydroxyapatite (HAp), two kinds of zinc-containing HAp, which had zinc content of 5.10wt% and 2.54wt%, respectively, were synthesized via sol-gel technique. The obtained coatings were characterized by X-ray diffraction (XRD) and scanning electron microscope (SEM). Then the antibacterial effects were evaluated through bacteriostatic test on Streptococcus mutans (S.mutans) in vitro and zinc ions releasing ability was investigated through detecting the zinc ions concentration by inductively coupled plasma-atomic emission spectroscopy (ICP-AES). The obtained coatings were observed to possess typical apatite peaks in XRD patterns and high homogeneous and porous surfaces in SEM morphology. The coating layer demonstrated good releasing ability in Brain Heart Infusion (BHI) liquid and obviously inhibitory effects to the growth and proliferation of S. mutans. Based on the results obtained above, it is concluded that the sol-gel derived zinc-containing hydroxyapatite could be applied as an antibacterial effective biomaterial.

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Periodical:

Key Engineering Materials (Volumes 361-363)

Pages:

139-142

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.361-363.139

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Online since:

November 2007

Authors:

Xin Chang Shi, H.Z. Jiang, J. Xue, Yun Mao Liao, L.Y. Xiao, C.Y. Bao, W. Li

Keywords:

Antimicrobial, Coating, Hydroxyapatite (HAP), Sol-Gel Route, Streptococcus mutans, Zinc Containing

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