Physical health levels of 95 married couples (group A), who live in the suburbs of big city, and 202 married couples (group B), who live in a local city of Kanto district, were measured using a health questionnaire, the Todai Health Index (THI). The male subject of both groups are workers of private company and the average age is early forties. This research was focused on the effect of smoking and place of residence on subjective complaints. Mean values of scale scores of couples' respiratory symptoms and husbands' digestive symptoms of group A were statistically higher than those of group B by the two-way analysis of variance. But no difference was recognized by the degree of smoking. Interactions existed on the effect of smoking and place of residence on the mean values of scale scores of wives' respiratory and digestive symptoms. These results indicate that respiratory symptoms and husbands' digestive symptoms increase by the modernization, but the effect of smoking habit on respiratory and digestive symptoms were relatively small.