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The chemopreventive potential and anti-inflammatory activities of Korean black ginseng in colon26-M3.1 carcinoma cells and macrophages

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Abstract

We investigated the chemopreventive and anti-inflammatory activity of Korean black ginseng (BG) in colon26-M3.1 carcinoma cells and macrophages (in vitro) compared with white ginseng (WG). Both WG and BG had no significant inhibitory effect on normal splenocytes, but on colon26-M3.1 carcinoma cells, BG showed significantly greater inhibitory effect than that of WG. Treating with either WG or BG extracts, the release of TNF-α was significantly decreased in response to lipopolysaccharide as compared with untreated control.

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Authors and Affiliations

  1. Department of Food and Nutrition, Hyejeon College, 350-702, Hongseong, Republic of Korea

    Ae-Jung Kim

  2. Department of Oriental Medicine Resources, Joongbu University, 312-702, Keumsan, Republic of Korea

    Shin-Jyung Kang

  3. Department of Food Service Management, College of Hotel and Tourism Management, Kyung Hee University, 130-701, Seoul, Republic of Korea

    Kyung-Hee Lee

  4. Department of Food and Nutrition, Sungshin Women’s University, 130-742, Seoul, Republic of Korea

    Myungsook Lee

  5. Department of Food Science and Technology, Chungang University, 456-756, Anseong, Republic of Korea

    Sang-Do Ha

  6. Department of Food Science and Human Nutrition and Research Institute of Human Ecology, Chonbuk National University, 561-756, Chonju, Republic of Korea

    Youn-Soo Cha

  7. Graduate School of East-West Medical Science, KyungHee University, 449-701, Yongin, Republic of Korea

    Sun Yeou Kim

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  1. Ae-Jung Kim
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  2. Shin-Jyung Kang
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  3. Kyung-Hee Lee
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  4. Myungsook Lee
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Correspondence to Ae-Jung Kim.

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Kim, AJ., Kang, SJ., Lee, KH. et al. The chemopreventive potential and anti-inflammatory activities of Korean black ginseng in colon26-M3.1 carcinoma cells and macrophages. J. Korean Soc. Appl. Biol. Chem. 53, 101–105 (2010). https://doi.org/10.3839/jksabc.2010.017

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  • DOI: https://doi.org/10.3839/jksabc.2010.017

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