Abstract:
Objective A cross-sectional study was conducted to investigate sero-prevalence of IgG to pertussis toxin (PT) in healthy population in Chongqing,estimate incidence of pertussis and provide scientific evidence for pertussis control.Methods A total of 1 080 healthy residents in 6 age groups were selected with stratified sampling from 6 districts in Chongqing.A questionnaire survey was conducted among all the subjects and blood samples were taken from them for the test of IgG to PT.Results The overall positive rate of anti PT IgG was 1.17%(11/944) with the mean concentration of 5.53 IU/ml,the highest antibody level was detected in age group 15 years (F=1.48,P=0.19).Conclusion This study found that Bordetella pertussis infection rate was actually high in healthy population in 6 districts of Chongqing,especially in age group 15 years,indicating that the incidence of pertussis might been underestimated in Chongqing and suggesting that it is necessary to improve the sensitivity of current pertussis surveillance system.