Abstract
Prolactin is released in response to physical and psychological stress, the latter of which involves an animal’s interpretation of its environment as potentially dangerous. This interpretation might be altered by social buffering, as defined by the presence of a social partner. In support of this claim, I previously found that the presence of a conspecific during exposure to the open field caused lower levels of prolactin in juvenile rats than did exposure to the open field alone. Because testing with a conspecific allowed the animals to touch, physical contact may have been necessary for the reduction of prolactin. To test this hypothesis, juvenile male and female rats in the present study were exposed to the open field (1) alone, (2) with a conspecific separated by a Plexiglas partition, or (3) with a conspecific without a partition. Touch was necessary to reduce stress as measured by prolactin levels.
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Abel, E. L. (1993). Physiological correlates of the forced swim test in rats. Physiology & Behavior, 54, 309–317.
Armario, A., Gil, M., Marti, J., Pol, O., & Balasch, J. (1991). Influence of various acute stressors on the activity of adult male rats in a holeboard and in the forced swim test. Pharmacology, Biochemistry & Behavior, 39, 373–377.
Armario, A., Lopez-Calderon, A., Jolin, T., & Balasch, J. (1986). Response of anterior pituitary hormones to chronic stress: The specificity of adaptation. Neuroscience & Biobehavioral Reviews, 10, 245–250.
Biondi, M., Pancheri, P., Falaschi, D., Teodori, A., Paga, G., Delle Chiaie, R., DiCasare, G., & Proietti, A. (1986). Social support as a moderator of the psychobiological stress response. New Trends in Experimental Clinical Psychiatry, 2, 173–183.
Biondi, M., & Picardi, A. (1999). Psychological stress and neuroendocrine function in humans: The last two decades of research. Psychotherapy & Psychosomatics, 68, 114–150.
Briski, K. P., & Sylvester, P. W. (1987). Effects of repetitive daily acute stress on pituitary LH and prolactin release during exposure to the same stressor or a second novel stress. Psychoneuroendocrinology, 12, 429–437.
Brown, K. J., & Grunberg, N. E. (1995). Effects of housing on male and female rats: Crowding stresses males but calms females. Physiology & Behavior, 58, 1085–1089.
Castro, W. L. R., & Matt, K. S. (1997). The importance of social condition in the hormonal and behavioral responses to an acute social stressor in the male Siberian dwarf hamster (Phodopus sungorus). Hormones & Behavior, 32, 209–216.
Dijkstra, H., Tilders, F. J., Hiehle, M. A., & Smelik, P. G. (1992). Hormonal reactions to fighting in rat colonies: Prolactin rises during defence, not during offence. Physiology & Behavior, 51, 961–968.
Freeman, M. E., Kanyicska, B., Lerant, A., & Nagy,G. (2000). Prolactin: Structure, function, and regulation of secretion. Physiological Reviews, 80, 1523–1631.
Gambardella, P., Greco, A. M., Sticchi, R., Bellotti, R., & Di Renzo,G. (1994). Individual housing modulates daily rhythms of hypothalamic catecholaminergic system and circulating hormones in adult male rats. Chronobiology International, 11, 213–221.
Gerritsen, W., Heijnen, C. J., Weigant, V. M., Bermond, B., & Frijda, N.H. (1996). Experimental social fear: Immunological, hormonal, and autonomic concomitants. Psychosomatic Medicine, 58, 273–286.
Hennessy, M. B. (1986). Effects of social partners on pituitary-adrenal activity during novelty exposure in adult female squirrel monkeys. Physiology & Behavior, 38, 803–807.
Kant, G. J., Bauman, R. A., Anderson, S. M., & Mougey, E. H. (1992). Effects of controllable vs. uncontrollable chronic stress on stressresponsive plasma hormones. Physiology & Behavior, 51, 1285–1288.
Kirschbaum, C., Klauer, T., Filipp, S. H., & Hellhammer, D. H. (1995). Sex-specific effects of social support on cortisol and subjective responses to acute psychological stress. Psychosomatic Medicine, 57, 23–31.
Levine, S., Lyons, D. M., & Schatzberg, A. F. (1997). Psychobiological consequences of social relationships. In C. S. Carter, I. I. Lederhendler, & B. Kirkpatrick (Eds.), The integrative neurobiology of affiliation (Annals of the New York Academy of Sciences, Vol. 807, pp. 210–218). New York: New York Academy of Sciences.
Lyons, D. M., Ha, C. M. G., & Levine, S. (1995). Social effects and circadian rhythms in squirrel monkey pituitary-adrenal activity. Hormones & Behavior, 29, 177–190.
Panksepp, J., & Beatty, W. W. (1980). Social deprivation and play in rats. Behavioral & Neural Biology, 30, 197–206.
Paris, J. M., Lorens, S. A., Van de Kar, L. D., Urban, J. H., Richardson-Morton, K. D., & Bethea, C. L. (1987). A comparison of acute stress paradigms: Hormonal responses and hypothalamic serotonin. Physiology & Behavior, 39, 33–43.
Richard-Yris, M. A., Sharp, P. J., Wauters, A. M., Guemene, D., Richard, J. P., & Foraste,M. (1998). Influence of stimuli from chicks on behavior and concentrations of plasma prolactin and luteinizing hormone in incubating hens. Hormones & Behavior, 33, 139–148.
Stanton, M. E., Patterson, J. M., & Levine, S. (1985). Social influences on conditioned cortisol secretion in the squirrel monkey. Psychoneuroendocrinology, 10, 125–134.
Taylor, G. T. (1981). Fear and affiliation in domesticated male rats. Journal of Comparative & Physiological Psychology, 95, 685–693.
Thorsteinsson, E. B., James, J. E., & Gregg, M. E. (1998). Effects of video-relayed social support on hemodynamic reactivity and salivary cortisol during laboratory-based behavioral challenge. Health Psychology, 17, 436–444.
Uvnäs-Moberg, K. (1998). Oxytocin may mediate the benefits of positive social interactions and emotions. Psychoneuroendocrinology, 23, 819–835.
Wilson, J. H. (2000). A conspecific attenuates prolactin responses to the open field. Hormones & Behavior, 38, 39–43.
Yelvington, D. B., Weiss, G. K., & Ratner, A. (1984). Effects of corticosterone on the prolactin response to psychological and physical stress in rats. Life Sciences, 35, 1705–1711.
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This research was supported in part by Instrumentation and Laboratory Improvement Grant DUE-9751060 from the National Science Foundation.
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Wilson, J.H. Prolactin in rats is attenuated by conspecific touch in a novel environment. Cognitive, Affective, & Behavioral Neuroscience 1, 199–205 (2001). https://doi.org/10.3758/CABN.1.2.199
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DOI: https://doi.org/10.3758/CABN.1.2.199