Abstract
The effects of 8.0 mg/kg fluprazine hydrochloride on latencies to locate a buried food reward were examined. The drug had no effect on rats’ performance when the reward was placed on the surface of the apparatus, but it produced a marginally significant increase in latency when the reward was buried 4.0 cm deep. These results provide further evidence that fluprazine interferes in some way with normal olfactory function and that this impairment is not restricted to the processing of conspecific odors. It is suggested that a generalized olfactory impairment may contribute to the drug’s effects on copulatory and maternal behavior as well as on conspecific aggression.
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This research was partially supported by an Undergraduate Research Opportunities Program grant to the first author. The authors would like to thank Kevin Flannelly and Dick Lore for their comments on this paper.
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Thornton, A.E., Kemble, E.D. Effects of fluprazine hydrochloride on an olfactory discrimination in rats. Bull. Psychon. Soc. 24, 456–458 (1986). https://doi.org/10.3758/BF03330582
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DOI: https://doi.org/10.3758/BF03330582