Is Foetal Programming by Mismatched Pre- and Postnatal Nutrition Contributing to the Prevalence of Obesity in Nepal?

Prabhat Khanal; Mette Olaf Nielsen

doi:10.3746/pnf.2019.24.3.235

주제분류

...

저널정보

한국식품영양과학회
Preventive Nutrition and Food Science 학술저널
Preventive Nutrition and Food Science Vol.24 No.3
2019.9 235 - 244 (10page)
DOI : 10.3746/pnf.2019.24.3.235

저자정보

Prabhat Khanal (Nord University)
Mette Olaf Nielsen (University of Copenhagen)

이용수
내서재: 0

내서재에 추가
되었습니다. 내서재에서
삭제되었습니다.

초록·키워드

오류제보하기

Nepal and many developing countries are currently suffering from increased prevalence of obesity, type 2 diabetes, and other metabolic disorders. Unhealthy dietary habits and physical inactivity are traditionally considered as responsible factors for these disorders. The relatively new concept of foetal programming suggests that development of metabolic diseases later in life may be associated with poor nutritional status in utero, and such phenomenon could be amplified by subsequent exposure to unhealthy diets after birth. We suggest that foetal programming and mismatched nutritional situations during foetal and postnatal life are important causative factors for increased prevalence of obesity and metabolic disorders in Nepal. Issues highlighted in this paper may also be relevant to other developing countries with similar socioeconomic status. Undernutrition in foetal life can predispose for visceral fat deposition and may alter dietary preferences towards unhealthy diets, amplifying the risk of nutritional mismatch after birth; this can lead to metabolic disturbances in a number of pathways including glucose and lipid metabolism. Providing attention to early life nutrition could therefore be an important tool to reduce the prevalence of lifestyle diseases in Nepal. Future national health policies should thus include changes in research and intervention activities towards preventing averse early life nutritional programming. Availability of free-of-cost and mandatory nutritional education and medical services to pregnant women and their families and better management of national health care systems including digitalization of national health data could be viable strategies to achieve these goals.

#foetal programming #metabolic disorder #nutrition #Nepal #obesity

ABSTRACT
INTRODUCTION
OVERWEIGHT AND OBESITY TRENDS IN NEPAL
CAUSES OF THE OBESITY PROBLEM IN NEPAL
FMP AND POSTNATAL ADIPOSE TISSUE DEPOSITION
FMP AND EATING PREFERENCES
FMP AND METABOLIC FUNCTION
FUTURE PERSPECTIVES/RECOMMENDATIONS
RESEARCH FOCUS
NUTRITIONAL STRATEGIES DURING PREGNANCY, AT BIRTH AND DURING EARLY POSTNATAL LIFE
NATIONAL HEALTH DATA MANAGEMENT SYSTEM
CONCLUSION
REFERENCES