Corticoterapia sistémica em Otorrinolaringologia
DOI:
https://doi.org/10.34631/sporl.817Palavras-chave:
corticosteróides, paralisia facial periférica idiopática, rinossinusite, otite média com efusão, hipoacusia súbita neurossensorial idiopática, neuronite vestibular, edema laríngeoResumo
Objetivos: Recapitular as propriedades farmacológicas dos corticosteroides (CCT) e abordar as principais aplicações da corticoterapia sistémica em Otorrinolaringologia.
Desenho do estudo: Revisão da literatura.
Material e métodos: Pesquisa de artigos na base de dados Pubmed, acerca de corticoterapia sistémica. Os estudos com relevância para a prática clínica em Otorrinolaringologia foram selecionados e a sua análise foi concluída em abril/2020.
Resultados e conclusões: A ação abrangente dos CCT deve-se à sua atividade intracelular e está associada a efeitos adversos que são dependentes da dose, tempo de tratamento e via de administração. Os CCT diferem entre si na atividade anti-inflamatória, duração de ação e presença de efeito mineralocorticóide. O uso de CCT varia entre Otorrinolaringologistas e parece estar relacionado com a experiência individual de cada um. A prescrição de CCT sistémicos deve ser criteriosa e individualizada, tendo em conta a patologia, as comorbilidades do doente e as propriedades farmacocinéticas dos CCT.
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Direitos de Autor (c) 2020 Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço
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