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Submitted: 31 Jul 2021
Revision: 12 Jan 2022
Accepted: 15 Jan 2022
ePublished: 01 Apr 2022
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Dis Diagn. 2022;11(2): 86-90.
doi: 10.34172/ddj.2022.16
  Abstract View: 341
  PDF Download: 245

Original Article

Iron Status in Patients With Chronic Left Ventricular Systolic Failure

Mitra Kazmi Jahromi 1 ORCID logo, Fatemeh Nikparvar 2 ORCID logo, Mansooreh Hoghooghi 3 ORCID logo, Shima Minaee 4 ORCID logo, Marzieh Nikparvar 5* ORCID logo, Elham Boushehri 6 ORCID logo, Mohsen Arabi 7 ORCID logo

1 Clinical Research Development Center of Shahid Mohammadi Hospital, Bandar Abbas, Iran.
2 Student Research Committee, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
3 Department of Medical Oncology and Hematology, Hormozgan University, Bandar Abbas, Iran.
4 Department of Cardiovascular Diseases, Razavi Hospital, Mashhad, Iran.
5 Cardiovascular Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
6 Medical Education, Health School, Hormozgan University of Medical Science, Bandar Abbas, Iran.
7 Department of Family Medicine, Iran University of Medical Sciences, Tehran, Iran.
*Corresponding Author: *Correspondence to Marzieh Nikparvar, Cardiovascular Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. Tel: 09171630209 Email:, Email: Nikparvarheart1@gmail.com

Abstract

Background: Heart failure is one of the most important public health problems with an increasing prevalence and identifying its contributing factors is imperative. This study was conducted to evaluate the iron status in patients with chronic systolic heart failure in Shahid Mohammadi Hospital of Bandar Abbas.

Materials and Methods: A total of 80 patients with chronic left ventricular failure participated in this cross-sectional study. Data were collected using a researcher developed checklist containing demographic details and echocardiographic data (left ventricular ejection fraction, LVEF%). Additionally, the frequency and distribution of iron status were measured in the research population.

Results: The results showed that the prevalence of anemia was significantly high in patients with chronic heart failure (77.3%). The prevalence of iron deficiency (ID) was 77.33% based on iron level (<60 μg/dL), and it was 82.66% based on the mean ferritin level (ferritin<100, or ferritin of 100 to 299 ng/mL, and transferrin saturation<20%). The prevalence of total iron binding capacity (TIBC)>360 μg/dL was 26.66%, and the prevalence of mean corpuscular volume (MCV)<80 fL was 60%. Age less than 60 years, glomerular filtration rate (GFR) less than 60, and body mass index (BMI) less than 18.5 were also found to increase the risk of anemia in these patients.

Conclusion: Our study showed that the prevalence of anemia was significantly high in patients with chronic heart failure. Due to the high prevalence of anemia in patients with chronic systolic heart failure and the impact of anemia on the prognosis of the disease in these patients, effective treatment is necessary in high-risk patients to reduce the severity of their disease, compensate for their heart failure, and reduce their mortality.

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