Estimulação cerebral profunda como tratamento na doença de Parkinson

Deep brain stimulation as a treatment in Parkinson's disease

Authors

  • Iasmin Ilce de Marselha Rodrigues
  • Daniel Rodrigues Lemos Neto
  • Felipe de Oliveira Souza
  • Jonathan Moreira Silva de Matos
  • Joyce Milena Arrais de Melo
  • Kamila Magalhães Souza
  • Natacha da Silva Estevão Cáceres Marques
  • Mônica Isaura Corrêa

DOI:

https://doi.org/10.34119/bjhrv5n5-118

Keywords:

doença de Parkinson, estimulação encefálica profunda, antiparkinsonianos

Abstract

O presente trabalho teve como objetivo detalhar a utilização da estimulação cerebral profunda (ECP) como estratégia terapêutica no tratamento da doença de Parkinson (DP) avançada. O diagnóstico da DP tem crescido de forma alarmante nas últimas décadas, sendo, atualmente, a principal desordem do movimento e segunda doença neurodegenerativa mais comum no mundo. O tratamento farmacológico para essa doença é bem estabelecido, porém ineficaz ou insuficiente em algumas situações. Nessas condições, outros métodos terapêuticos para tratar as complicações motoras são indicados, entre eles a ECP, que é uma forma de neuromodulação onde eletrodos, conectados a um gerador de pulso, são cirurgicamente implantados em alvos específicos do cérebro permitindo a articulação dos padrões de condução do potencial de ação dos neurônios até determinadas regiões. Trata-se de um recurso terapêutico seguro e efetivo, melhorando disfunções motoras e reduzindo tremores, além de permitir o ajuste adequado para cada indivíduo, restringindo os efeitos colaterais associados à medicação. Ainda, assim, o desenvolvimento de mais pesquisas sobre o tema é de grande importância de forma a tornar esse tratamento mais acessível, com maior previsibilidade no longo prazo, além de reduzir os principais riscos associados.

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Published

2022-09-19

How to Cite

RODRIGUES, I. I. de M.; NETO, D. R. L.; SOUZA, F. de O.; MATOS, J. M. S. de; MELO, J. M. A. de; SOUZA, K. M.; MARQUES, N. da S. E. C.; CORRÊA, M. I. Estimulação cerebral profunda como tratamento na doença de Parkinson : Deep brain stimulation as a treatment in Parkinson’s disease. Brazilian Journal of Health Review, [S. l.], v. 5, n. 5, p. 19052–19063, 2022. DOI: 10.34119/bjhrv5n5-118. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/52239. Acesso em: 28 mar. 2024.

Issue

Section

Original Papers