The Antioxidant Capacities of Natural Products 2019

The search for new natural antioxidants is a growing area of research due to the broad spectrum of their biological properties, which are associated with the prevention of chronic diseases that originate in oxidative stress [...].

and Reynoutria x bohemica [13], fruits of Lycium barbarum L. [14]), the pericarp of Dimocarpus longan Lour. [15], the resin of the tree species Croton lechleri (Müll. Arg) [16] and a herbal standardized product containing an extract of persimmon leaves [17]. In parallel, nonphenolic compounds, including monoterpes and their derivatives from three mentha species [18], alkaloids from Uncaria tomentosa [19], polysaccharides from white ginseng [20] and protein hydrolysates from walnut meal [21], were also demonstrated to hold the potential to be used as natural antioxidants and/or to fight oxidative stress related disorders.
Attention was also given to the impact of distinct factors on the levels of relevant natural compounds, including bioactive components of plants/vegetables. For example, the work of Liu et al. [22] demonstrated that sunny hours and temperature were the main drivers affecting the accumulation of Cyclocarya paliurus phenolics and their antioxidant properties. In addition, Guan and coworkers [23] concluded that the combination of methyl jasmonate treatment with wounding stress could stimulate phenolic accumulation in broccoli. Moreover, Pereira et al. [24] described the variable effects of commercial biostimulants and irrigation regimes on the chemical composition and bioactive properties of two spinach genotypes, alerting one to the need for further research in order to make solid conclusions on the effects of the use of biostimulants under water stress conditions.
The application of natural compounds as ingredients in novel products to emphasize specific characteristics or new strategies to improve the quality and antioxidant properties of health-promoting natural products/bioactive compounds were also addressed by some contributing authors. This included the formulation of a novel fermented glutinous rice product with the supplementation of Fu brick tea (i.e., a beverage processed through the postfermentation of Camellia sinensis L.) to increase its sensorial features, the levels of phenolics, and its antioxidant and DNA protective activities [25]; the supplementation of pasta flour with salmon fish powder to manipulate the glycaemic index, protein digestibility, release of phenolic compounds and antioxidant capacity of the digested pasta [26]; and the use of cold saponification on commercial natural soaps manufactured from plant oils and additives in order to retain unsaponified fatty acids, phenolic compounds and antioxidant activities in the final products [27]. In addition, Wu et al. [28] explored a new strategy for ameliorating the stability and enhancing the stability, solubility and safety of resveratrol through the preparation of novel resveratrol transfersomes.
Campos et al. [29] provided an overview on the valorization of fruit byproducts from food-processing industries in order to overcome a global problem, highlighting the application of sustainable and green methodologies for the conversion of fruit waste into high-value products with a significant biological activity. Santos and Silva [30] summarized different prenylation patterns of natural and synthetic flavonoids that have been focused on in the past two decades, aiming at the elucidation of structure-antioxidant activity relationships and the development of efficient routes for the synthesis of natural derivatives. All of the studies published over the last decade on the relationship between moderate alcohol consumption and coronary heart disease were revised by Castaldo et al. [31], who summarized the various red wine components and the putative mechanisms that influence their activity. Cione et al. [32] described four polyphenols used as nutritional supplements: quercetin, epigallocatechin gallate, curcumin and resveratrol, summarizing the current knowledge about them, ranging from dietary sources to human microRNA modulation.
Acknowledgments: The Guest Editors wish to thank all the authors for their contributions to this Special Issue, all the reviewers for their work in evaluating the submitted articles, and the editorial staff of Molecules for their kind assistance.

Conflicts of Interest:
The authors declare no conflict of interest.