J Appl Biomed 2:179-185, 2004 | DOI: 10.32725/jab.2004.021

Chronohaematology

Josef Berger
Faculty of Health and Social Studies, University of South Bohemia in České Budějovice, Czech Republic

Rhythmic changes in a number of haematological characteristics have been described in many published papers during the 20th and at the beginning of the 21st century. The best known are circadian rhythms, which are mostly correlated with the light/dark regime, inducing rhythmic changes in levels of melatonin, synchronised by a suprachiasmatic nucleus and the retinohypothalamic input. These circadian rhythms in men and diurnal animals have an inverse relationship to rhythms in nocturnal beings. Some haematological rhythms are modified by other synchronisers. Knowledge of circadian rhythms in haematological characteristics is important for both the faultless clinical interpretation of laboratory data and the search for mechanisms participating in rhythm regulation.

Keywords: circadian rhythm; blood cell; haemopoiesis; clinical significance; synchronization

Received: August 18, 2004; Revised: October 29, 2004; Published: July 31, 2004  Show citation

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Berger J. Chronohaematology. J Appl Biomed. 2004;2(4):179-185. doi: 10.32725/jab.2004.021.
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