EVALUATION OF THE INFLUENCE OF MULTIPLE PATERNITY ON THE IMMUNE STATUS OF SYRIAN HAMSTER (MESOCRICETUS AURATUS, CRICETIDAE, RODENTIA) YOUNG

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Abstract

The effect of multiple paternity on the development of the humoral immune response in Syrian hamster pups was studied. The paternity type was found to be determined by 10 microsatellite markers. Pups were immunized with T-dependent antigens (fissurella hemocyanin, KLH) at 33 days of age, with the level of specific antibodies (anti-KLH IgG) measured in blood samples at 5, 10, 20 and 25 days after immunization. As much as 24% pups from multiple paternity litters and 25% from single paternity litters were revealed to develop no immune response. At the same time, in all pups that responded to immunization, the level of anti-KLH IgG significantly increased over time, starting with the 5th day after immunization. However, there were significant differences in the concentration of anti-KLH IgG in the blood serum of pups derived neither from litters with multiple paternity nor litters obtained from one male. Therefore, our results fail to support the hypothesis that multiple paternity enhances the immunity of Syrian hamster pups.

About the authors

E. V. Potashnikova

Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences

Author for correspondence.
Email: potashnikova.k@gmail.com
Russia, 119071, Moscow, Leninsky Prospect, 33

E. V. Kuznetsova

Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences

Author for correspondence.
Email: kuznetsovaekvl@gmail.com
Russia, 119071, Moscow, Leninsky Prospect, 33

N. Yu. Feoktistova

Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences

Author for correspondence.
Email: feoktistovanyu@gmail.com
Russia, 119071, Moscow, Leninsky Prospect, 33

N. A. Vasilieva

Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences

Author for correspondence.
Email: ninavasilieva@gmail.com
Russia, 119071, Moscow, Leninsky Prospect, 33

S. I. Meshcherskii

Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences

Author for correspondence.
Email: nervaner6892236@gmail.com
Russia, 119071, Moscow, Leninsky Prospect, 33

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