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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A Review of Cost of Ilness Studies in Chronic Kidney Disease Patients with Multiple Components of Medication Treatment

Author: ENDANG SUNARIYANTI, TRI MURTI ANDAYANI, DWI ENDARTI, DIAH AYU PUSPANDARI
Abstract: The prevalence of chronic kidney disease is currently increasing significantly and has become a serious health problem. Ten percent of the world population has chronic kidney disease and millions die every year because they do not have access to treatment. Currently in Indonesia, there is a high prevalence of chronic kidney disease with high costs of medical treatment incurred by patients.Some of the medical cost components incurred by patients withchronic kidney disease are in-patient and out-patient care, drug costs, laboratory costs, physician services,home care, hemodialysis, etc. This article aimed to present a systematic review of the cost components incurred by patients with chronic kidney diseases. The search for articles was done throughGoogle ScholarandPubMedfor one month since August 2019. The researchers used keywords such as cost of illness, cost of disease, chronic kidney disease, direct medical cost,etc.For the selection of articles, the researchers used PRISMA diagrams. The inclusion criteria were original research, accessible in full text, published in the last 10 years, discussingthe medical cost components of kidney diseases. There were 17 articles which met the inclusion criteria and 71 were excluded. Our findings showed that the costs of inpatient care, drugs, and hemodialysis were the cost components with large contribution (>50%) compared to other cost components. The total medical costs incurred by chronic kidney disease patients with comorbidities and complications (cardiovascular diseases and diabetes mellitus) are higher than those incurred by patientswithout comorbidities/complications. In fact, the medical costs increase along with the severity of the diseases. These results can be an input for policy makers and hospital management to allocate effective and efficient funding, especially for patients with chronic kidney diseases.
Keyword: Cost analysis, chronic kidney disease, systematic review.
DOI: https://doi.org/10.31838/ijpr/2021.13.02.115
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