MMSL 2016, 85(1):19-30 | DOI: 10.31482/mmsl.2016.004

HUMULUS LUPULUS L. (HOPS) - A VALUABLE SOURCE OF COMPOUNDS WITH BIOACTIVE EFFECTS FOR FUTURE THERAPIESReview article

Jana Olšovská1, Vanda Boštíková ORCID...2*, Martin Dušek1, Vladimíra Jandovská1,5, Kateřina Bogdanová4, Pavel Čermák3, Pavel Boštík ORCID...2, Alexandr Mikyska1, Milan Kolář4
1 Research Institute of Brewing and Malting, Prague, Czech Republic
2 Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
3 Department of Clinical Microbiology, Thomayer Hospital, Prague, Czech Republic
4 Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic
5 Faculty of Science, Charles University, Prague, Czech Republic

Hops are a well-known source of resins, essential oils and polyphenolic substances, such as proanthocyanidins or prenylflavonoids with significant representatives of xanthohumol, isoxanthohumol, and 8-prenylnaringenine, and represent an essential ingredient in beer production. Recently, however, many additional bioactive effects of hop compounds have been investigated.A systematic review of the structure-function relationship between the individual hop-derived compounds and their bio-activity has been lacking. In this review we summarize some recent findings in this area from reports from our as well as other studies. It shows multiple bio-medical effects of the individual hop derived compounds, which can act individually, or in a synergistic manner.The hops can serve as a source of bio-active compounds in phyto-medicine and as such, more attention and detailed studies are warranted to utilize the broad spectrum of effects of individual compounds in future treatments.

Keywords: Humulus lupulus L.; hops; hop resins; hop oils; hop polyphenols; bioactive effects

Received: January 11, 2016; Revised: February 20, 2016; Published: March 4, 2016  Show citation

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Olšovská, J., Boštíková, V., Dušek, M., Jandovská, V., Bogdanová, K., Čermák, P., ... Kolář, M. (2016). HUMULUS LUPULUS L. (HOPS) - A VALUABLE SOURCE OF COMPOUNDS WITH BIOACTIVE EFFECTS FOR FUTURE THERAPIES. MMSL, 85(1), 19-30. doi: 10.31482/mmsl.2016.004
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