Practical approach to the use of corticosteroids in patients with uveitisa,b
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2022, Survey of OphthalmologyCitation Excerpt :Current strategies aim to prevent additional ocular damage and vision loss by reducing intraocular inflammation31; such strategies comprise the use of anti-inflammatory agents following a stepladder approach.37 While immunomodulatory agents and biologic response modifiers are now available for the treatment of uveitis,18 corticosteroids are still often the first line treatment in acute noninfectious disease10; however, systemic corticosteroids are associated with adverse effects that are dose- and duration-dependent, such as hyperglycemia, myopathy and secondary infections.11,49 Such side effects are not observed with regional corticosteroids,34,49 which can be injected in the vitreous or in periocular sites.
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2020, Acta BiomaterialiaCitation Excerpt :As a result, the frequency of drop administration is increased to provide tissues with therapeutic drug levels. For non-infectious inflammatory conditions like acute uveitis, steroid eye drops are commonly prescribed hourly [2,10]. Understandably, patient adherence with such intensive treatment regimens can be difficult.
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- a
Presented in part at the Canadian Ophthalmological Society Annual Meeting, Quebec, Que., June 26–29, 2010
- b
This article has been peer-reviewed.