ABSTRACT
INTRODUCTION Anxiety and depression have become recognized as common nonmotor, psychiatric comorbidities in idiopathic Parkinson’s disease (PD), which contribute to additional disability such as significant impairments of cognitive, functional, motor, and social performance. This leads to reductions in quality of life and increased caregiver distress (1-8). Preliminary data suggest that depression may be an independent predictor of mortality in patients with PD (9). However, these affective disorders are under-recognized and under-treated in patients with PD due to symptom overlap with motor and cognitive features of PD (10-12).
