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Evaluation the Effect of Zilpaterol Hydrochloride Levels and Feeding Methods on Meat Quality and Performance of Female Broiler Chickens

  • ANIMAL SCIENCE AND VETERINARY MEDICINE
  • Published:
Russian Agricultural Sciences Aims and scope

Abstract

This study aimed to investigate the effects of different levels of dietary Zilpaterol Hydrochloride (ZH) and feeding methods on growth performance, carcass characteristics, and blood parameters in Ross female broiler chickens. For this, 200 female broilers Ross 308 with 25 days age were assigned to eight treatments. A factorial arrangement comprising four ZH doses (0, 0.2, 0.25, and 0.3 mg zilpaterol/kg of live weight–1) and two feeding methods of ZH supplementation (daily or every two days) was applied. In general, the Feed Conversion Ratio (FCR) of birds significantly improved (P < 0.05) with ZH in comparison with the control group (P < 0.05). There was no significant difference in weight gain among all tested animals (P > 0.05). Administration of ZH significantly increased the relative weight of leg muscle and reduced abdominal fat compared to the control treatment (P < 0.05). While dry matter, ash, and tissue fat had not changed (P < 0.05) leg muscle protein and fat of ZH-treated birds were higher and lower than the control group, respectively (P < 0.05). In comparison with the control group, only addition of 0.3 mg ZH decreased the cholesterol value of plasma (P < 0.05). Overall, the results demonstrated that zilpaterol hydrochloride fed at the finishing period enhances the growth performance of female broiler chickens and the most economical dose of ZH was 0.25 mg when added every two days.

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REFERENCES

  1. Samuelson, K.L., Hubbert, M.E., and Löest, C.A., Effects of dietary urea concentration and zilpaterol hydrochloride on performance and carcass characteristics of finishing steers, J. Anim. Sci., 2016, vol. 94, no. 12, pp. 5350–5358.

    Article  CAS  Google Scholar 

  2. Rojo-Rubio, R., Avendaño-Reyes, L., Albarrán, B., Vázquez, J.F., Soto-Navarro, S.A., Guerra, J., and Macías-Cruz, U., Zilpaterol hydrochloride improves growth performance and carcass traits without affecting wholesale cut yields of hair sheep finished in feedlot, J. Appl. Anim. Res., 2018, vol. 46, no. 1, pp. 375–379.

    Article  CAS  Google Scholar 

  3. Trotta, R.J., Maddock Carlin, K.R., and Swanson, K.C., Effects of ractopamine hydrochloride supplementation on feeding behavior, growth performance, and carcass characteristics of finishing steers, Transl. Anim. Sci., 2019, vol. 3, no. 4, pp. 1143–1152.

    Article  Google Scholar 

  4. Valladares-Carranza, B., Velázquez-Ordoñez, V., Zamora-Espinosa, J.L., Aviles-Martínez, J.A., Zaragoza-Bastida, A., and Posadas-Sánchez, M.A., Implications of the use of clenbuterol hydrochloride in beef cattle, in Nutritional Strategies of Animal Feed Additives, New York: Nova Science, 2013, pp. 185–196.

    Google Scholar 

  5. Carr, S.N., Rincker, P.J., Killefer, J., Baker, D.H., Ellis, M., and McKeith, F.K., Effects of different cereal grains and ractopamine hydrochloride on performance, carcass characteristics, and fat quality in late- finishing pigs, J. Anim. Sci., 2005, vol. 83, no. 1, pp. 223–230.

    Article  CAS  Google Scholar 

  6. Apple, J.K., Maxwell, C.V., Sawyer, J.T., Kutz, B.R., Rakes, L.K., Davis, M.E., Johnson, Z.B., Carr, S.N., and Armstrong, T.A., Interactive effect of ractopamine and dietary fat source on quality characteristics of fresh pork bellies, J. Anim. Sci., 2007, vol. 85, no. 1, pp. 2682–2690.

    Article  CAS  Google Scholar 

  7. Allen, J.D., Ahola, J.K., Chahine, M., Szasz, J.I., Hunt, C.W., Schneider, C.S., and Hill, R.A., Effect of preslaughter feeding and ractopamine hydrochloride supplementation on growth performance, carcass characteristics, and end product quality in market dairy cows, J. Anim. Sci., 2009, vol. 87, no. 7, pp. 2400–2408.

    Article  CAS  Google Scholar 

  8. Poletto, R., Rostagno, M.H., Richert, B.T., and Marchant-Forde, J.N., Effects of a “step-up” ractopamine feeding program, sex, and social rank on growth performance, hoof lesions, and Enterobacteriaceae shedding in finishing pigs, J. Anim. Sci., 2009, vol. 87, no. 1, pp. 304–313.

    Article  CAS  Google Scholar 

  9. Hatefi, A., Towhidi, A., Zali, A., Zeinoaldini, S., Ganjkhanlou, M., Masoudi, R., and Plascencia, A., Influence of dietary zilpaterol hydrochloride on feedlot performance, carcass traits, chemical composition of longissimus muscle, and plasma metabolites of castrated male goats, Turk. J. Vet. Anim. Sci., 2015, vol. 39, no. 2, pp. 195–202.

    Article  CAS  Google Scholar 

  10. López-Carlos, M.A., Ramírez, R.G., Aguilera-Soto, J.I., Aréchiga, C.F., Méndez-Llorente, F., Rodríguez, H., and Silva, J.M., Effect of ractopamine hydrochloride and zilpaterol hydrochloride on growth, diet digestibility, intake and carcass characteristics of feedlot lambs, Livest. Sci., 2010, vol. 131, no. 1, pp. 23–30.

    Article  Google Scholar 

  11. Lamming. G.E., Effect of beta-agonists on animal growth and carcass quality: summary and perspective, in Beta-Agonists and Their Effects on Animal Growth and Carcass Quality, Hanrahan, J.P., Ed., Amsterdam: Elsevier, 1988.

    Google Scholar 

  12. Dib, M.G., Strategies for beef cattle adaptation to finishing diets, ractopamine hydrochloride utilization, and mature size genetic selection, MSc Thesis, Lincoln: Univ. of Nebraska, 2010.

  13. Mohammadi-Arekhlo, M., Towhidi, A., Moravej, H., and Sharafi, M., Effect of different zilpaterol hydrochloride levels and feeding methods on the growth performance, carcass traits and blood parameters of male japanese quails during two weeks of the finishing period, Braz. J. Poult. Sci., 2015, vol. 17, no. 4, pp. 567–574.

    Article  Google Scholar 

  14. Jones, R.W., Easter, R.A., McKeith, F.K., Dalrymple, R.H., Maddock, H.M., and Bechtel, P.J., Effect of the β-adrenergic agonist cimaterol (CL 263,780) on the growth and carcass characteristics of finishing swine, J. Anim. Sci., 1985, vol. 61, no. 4, pp. 905–913.

    Article  CAS  Google Scholar 

  15. Kim, Y.S., Lee, Y.B., Ashmore, C.R., and Han, I.K., Effects of cimaterol on carcass and skeletal muscle characteristics under ad libitum and restricted feeding conditions in lambs, Asian-Australas. J. Anim. Sci., 1988, vol. 1, no. 4, pp. 223–232.

    Article  Google Scholar 

  16. Beermann, D.H., Hogue, D.E., Fishell, V.K., Dalrymple, R.H., and Ricks, C.A., Effects of cimaterol and fishmeal on performance, carcass characteristics and skeletal muscle growth in lambs, J. Anim. Sci., 1986, vol. 62, no. 2, pp. 370–380.

    Article  CAS  Google Scholar 

  17. Galbraith, H., Minassie, B., and Scaife, J.R., Effect of the β-adrenergic agonist cimaterol and dietary protein level on fat young sheep given diets containing submaintenance levels of dietary energy, J. Anim. Sci., 1997, vol. 64, no. 2, pp. 271–278.

    Article  CAS  Google Scholar 

  18. Official Methods of Analysis, Washington DC: Assoc. Off. Anal. Chem., 1990, 15th ed.

  19. Montgomery, J.L., Krehbiel, C.R., Cranston, J.J., Yates, D.A., Hutcheson, J.P., Nichols, W.T., and Montgomery, T.H., Dietary zilpaterol hydrochloride. I. Feedlot performance and carcass traits of steers and heifers, J. Anim. Sci., 2009, vol. 87, no. 4, pp. 1374–1383.

    Article  CAS  Google Scholar 

  20. Avendaño-Reyes, L., Torres-Rodríguez, V., Meraz-Murillo, F.J., Pérez-Linares, C., Figueroa-Saavedra, F., and Robinson, P.H., Effects of two β-adrenergic agonists on finishing performance, carcass characteristics, and meat quality of feedlot steers, J. Anim. Sci., 2006, vol. 84, no. 12, pp. 3259–3265.

    Article  Google Scholar 

  21. Kheiri, F., Pourreza, J., Ebrahimnezhad, Y., Nazeradl, K., and Haji-abadi, S.M.A.J., Effects of supplemental ractopamine and L-carnitine on growth performance, blood biochemical parameters and carcass traits of male broiler chicks, Afr. J. Biotechnol., 2011, vol. 10, no. 68, pp. 15450–15455.

    Article  CAS  Google Scholar 

  22. Ansari-Pirsaraei, Z., Abolghasemi, A., Jafari-Sayadi, A., and Jalali-Hajiabadi, M., Effect of terbutaline feeding on some blood parameters and carcass characteristics in broiler chicks, Proc. 16th Eur. Symp. on Poultry Nutrition, Strasbourg, 2007.

  23. Estrada-Angulo, A., Barreras-Serrano, A., Contreras, G., Obregon, J.F., Robles-Estrada, J.C., Plascencia, A., and Zinn, R.A., Influence of level of zilpaterol chlorhydrate supplementation on growth performance and carcass characteristics of feedlot lambs, Small Ruminant Res., 2008, vol. 80, nos. 1–3, pp. 107–110.

    Article  Google Scholar 

  24. Morgan, J.B., Jones, S.J., and Calkins, C.R., Muscle protein turnover and tenderness in broiler chickens fed cimaterol, J. Anim. Sci., 1989, vol. 67, no. 10, pp. 2646–2654.

    Article  CAS  Google Scholar 

  25. Muramatsu, T., Kakita, M., Aoyagi, Y., and Okumura, J., Research note: β-adrenergic agonist effects on liver and breast muscle protein synthesis in female chicks, Poult. Sci., 1991, vol. 70, no. 77, pp. 1630–1632.

    Article  Google Scholar 

  26. Robles-Estrada, J.C., Arrizon, A.A., Barreras, A., Calderon, J.F., Figueroa-Saavedra, F., Torrentera, N., and Zinn, R.A., Effects of preslaughter withdrawal period on response of feedlot heifers to zilpaterol 303 hydrochloride supplementation: Growth performance and carcass characteristics, J. Anim. Sci., 2009, vol. 87, no. 5, pp. 1759–1763.

    Article  CAS  Google Scholar 

  27. DeClerck, J.C., Lucherk, L.W., Reeves, N.R., Miller, M.F., Bernhard, B.C., and Rathmann, R.J., Influence of ractopamine hydrochloride and days on feed on feedlot performance and red meat yield in thin cull beef cows targeted for a lean market, Transl. Anim. Sci., 2020, vol. 4, no. 1, pp. 170–181.

    Article  Google Scholar 

  28. Holmer, S.F., Fernández-Dueñas, D.M., Scramlin, S.M., Souza, C.M., Boler, D.D., McKeith, F., and VanOverbeke., D.L., The effect of zilpaterol hydrochloride on meat quality of calf-fed Holstein steers, J. Anim. Sci., 2009, vol. 87, no. 11, pp. 3730–3738.

    Article  CAS  Google Scholar 

  29. Genther-Schroeder, O.N., Branine, M.E., and Hansen, S.L., Effects of increasing supplemental dietary Zn concentration on growth performance and carcass characteristics in finishing steers fed ractopamine hydrochloride, J. Anim. Sci., 2018, vol. 96, no. 5, pp. 1903–1913.

    Article  Google Scholar 

  30. Zamiri, M.J. and Izadifard, J., Effects of metaproterenol, a beta-adrenergic agonist, on feedlot performance and body composition of two fat-tailed breeds of sheep, Small Ruminant Res., 1995, vol. 18, no. 3, pp. 263–271.

    Article  Google Scholar 

  31. Needham, T., Hoffman, L.C., and Gous, R.M., Growth responses of entire and immunocastrated male pigs to dietary protein with and without ractopamine hydrochloride, Animal, 2017, vol. 11, no. 9, p. 1482–1487.

    Article  CAS  Google Scholar 

  32. Ferreira, M.S.D.S., Garbossa, C.A.P., Oberlender, G., Pereira, L.J., Zangeronimo, M.G., Sousa, R.V.D, and Cantarelli, V.D.S., Effect of ractopamine on lipid metabolism in vivo—a systematic review, Braz. Arch. Biol. Technol., 2013, vol. 56, no. 1, pp. 35–43.

    Article  CAS  Google Scholar 

  33. Zare Shahneh, A., Ali Beigi Nejhad, H., Rowghani, E., Eilami, B., and Rowghani, S., Effects of Salbutamol on growth performance and carcass characteristics of Japanese quail (Coturnix japonica), Iran. J. Vet. Res., 2012, vol. 13, no. 2, pp. 112–119.

    Google Scholar 

  34. Timmerman, H., Beta-Adrenergic; physiology, pharmacology, applications, structures and structure-activity relationships, in Beta-Agonists and Their Effects on Animal Growth and Carcass Quality, Hanrahan, J.P., Ed., London: Elsevier, 1988.

    Google Scholar 

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Authors and Affiliations

  1. Department of Animal Science, University of Tabriz, Tabriz, Iran

    S. A. Moftakharzadeh

  2. Medical physiology Department of Physiology Isfahan University of Medical Sciences, Isfahan, Iran

    H. Khirkhah

  3. Department of Animal Science, Agriculture and Natural Source Pardis, University of Tehran, Tehran, Iran

    A. Towhidi, Hossein Moravej & A. Hatefi

  4. Animal Science Research Institute of Iran (ASRI), Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran

    R. Masoudi

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  1. S. A. Moftakharzadeh
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  2. H. Khirkhah
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  4. Hossein Moravej
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Correspondence to S. A. Moftakharzadeh.

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Moftakharzadeh, S.A., Khirkhah, H., Towhidi, A. et al. Evaluation the Effect of Zilpaterol Hydrochloride Levels and Feeding Methods on Meat Quality and Performance of Female Broiler Chickens. Russ. Agricult. Sci. 47, 635–642 (2021). https://doi.org/10.3103/S1068367421060070

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  • DOI: https://doi.org/10.3103/S1068367421060070

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