Abstract
The results are obtained by simultaneous diagnostics of mutant CV- and BL-alleles. Five groups of animals–carriers and noncarriers of mutations are identified. In Russia the mutant CV-alleles are met more frequently because of the intensive use of their carriers. While elimination of BL-allele was started earlier due to developed methods, the diagnostics of CV-mutations has been undertaken later. Propagation of missense-mutations in the world and the Russian Federation has been occurring through the breeding bulls and cows–carriers. Initially spermobanks and, afterwards, cows were reserves for the diagnosed BLand CV-mutations.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
ICAR Guidelines Approved by the General Assembly Held in Riga, Latvia on June 2010, 2011.
Eskin, G.V., Turbina, I.S., Fedorova, E.V., Poluektova, G.A., Gus’kova, S.V., Kovaleva, L.N., Maksimchuk, G.G., Usmanova, N.N., Chistyakov, V.I., and Chaplin, A.I., Katalog bykov-proizvoditelei OAO GTsV (Catalog of Bull Sires of OAO GTsV), Moscow, 2014–2015.
Marzanova, S.N., Alekseev, Ya.I., Konovalova, N.V., Turbina, I.S., Devrishov, D.A., Sochivko, D.G., and Marzanov, N.S., Development of the method of diagnosis of complex vertebral malformation (CVM) by PCR in real time at the black-and-white cattle, Probl. Biol. Prod. Zhivotn., 2011, no. 4, pp. 79–82.
Schutz, E., Scharfenstein, M., and Brenig, B., Implication of complex vertebral malformation and bovine leukocyte adhesion deficiency DNA-based testing on disease frequency in the Holstein population, J. Dairy Sci., 2008, vol. 91, pp. 4854–4859.
Agerholm, J.S., Houe, H., Jorgensen, C.B., and Basse, A., Bovine leukocyte adhesion deficiency in Danish Holstein-Friesian cattle. II. Patho-anatomical description of affected calves, Acta Vet. Scand., 1993, vol. 34, pp. 237–243.
Agerholm, J.S., Anderson, O., Almskou, M.B., Bendixen, C., Arnbjerg, J., and Aamand, G.P., Evaluation of the inheritance of the complex vertebral malformation syndrome by breeding studies, Acta Vet. Scand., 2004, vol. 45, pp. 133–137.
Kehrli, Jr., M.E., Shuster, D.E., and Ackermann, M.R., Leukocyte adhesion deficiency among Holstein cattle, Cornell Vet., 1992, vol. 82, pp. 103–109.
Mayr, E., Change of genetic environment and evolution, in Evolution as a Process, Huxley, J., London: George Allen and Unwin, 1954.
Ignat’ev, V.M., Screening of gene leukocyte adhesion (BLAD-syndrome) in animals of black and white root cattle, Cand. Sci. (Biol.) Dissertation, Dubrovitsy, 1998.
Marzanov, N.S., Turbina, I.S., Eskin, G.V., Turbina, G.S., Ignat’ev, V.M., Popov, A.N., and Kharlitsius, B., Screening of the leukocyte adhesion deficiency gene in animals of the black-motley Holsteinized cattle, S-kh. Biol., 2003, no. 6, pp. 23–30.
Turbina, I.S., Feature sires for various genetic markers, Cand. Sci. (Biol.) Dissertation, Moscow, 2006.
Marzanova, S.N. The development of gene diagnostics of complex vertebral malformation (CVM) and immunodeficiency (BLAD) in the black-motley Holsteinized cattle, Cand. Sci. (Biol.) Dissertation, Moscow, 2012.
Marzanov, N.S., Eskin, G.V., Turbina, I.S., Devrishov, D.A., Tokhov, M.Kh., and Marzanova, S.N., Genodiagnostika i rasprostranenie allelya immunodefitsita, ili BLAD-sindroma, u cherno-pestroi porody krupnogo rogatogo skota (DNA Diagnostics and Distribution of Allele Immunodeficiency, or BLAD Syndrome, in the Black-Motley Cattle), Moscow: Rosinformagrotekh, 2013.
Dement’eva, N.V., Mitrofanova O.V., Tyshchenko V.I., Nikitkina E.V., Terletskii V.P., and Yakovlev A.F., Occurrence and significance of CVM mutation in breeding animals of the Leningrad Oblast, Molochn. Myasn. Skotovod. (Moscow), 2014, no. 6, pp. 7–9.
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © S.N. Marzanova, V.A. Nagorniy, D.A. Devrishov, Ya.I. Alekseev, N.V. Konovalova, M.Kh. Tokhov, G.V. Eskin, I.S. Turbina, A.A. Lukashina, N.S. Marzanov, 2015, published in Rossiiskaya Sel’skokhozyaistvennaya Nauka, 2015, No. 6, pp. 44–47.
About this article
Cite this article
Marzanova, S.N., Nagorniy, V.A., Devrishov, D.A. et al. Founder effect and genogeography of CV- and BL-mutations in black-and-white cattle. Russ. Agricult. Sci. 42, 90–93 (2016). https://doi.org/10.3103/S1068367416010134
Received:
Published:
Issue Date:
DOI: https://doi.org/10.3103/S1068367416010134