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Using confocal microscopy to study the effect of an original pro-enzyme Se/arabinogalactan nanocomposite on tissue regeneration in a skeletal system

  • Proceedings of the International Conference “Luminescence and Laser Physics, 2014”
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Bulletin of the Russian Academy of Sciences: Physics Aims and scope

Abstract

The effect an original nanocomposite of elemental selenium and arabinogalactan heteropolysaccharide has on the rate of the calcification of calluses in the case of a traumatic injury is studied experimentally using confocal and fluorescence microscopy. With a local increase in the selenium concentration in the area of the traumatic injury, we observe low intensity of mineralization for the forming callus and a slowing down of bone regeneration. The difficulties of visualizing fluorescent labels introduced simultaneously are discussed.

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References

  1. Misof, B.M., Gamsjaeger, S., Cohen, A., et al., J. Bone Miner. Res., 2012, vol. 27, no. 12, pp. 2551–2561. doi: 10.1002/jbmr.1699.

    Article  Google Scholar 

  2. Frost, M.L., Compston, J.E., Goldsmith, D., et al., Calcif. Tissue Int., 2013, vol. 93, pp. 436–447. doi: 10.1007/s00223-01309778-7.

    Article  Google Scholar 

  3. Shurygina, I.A., Shurygin, M.G., Rodionova, L.V., Lebedev, V.F., and Dremina, N.N., Bull. East-Siberian Acad. Med. Sci., 2012, vol. 5, no. 2, pp. 120–122.

    Google Scholar 

  4. Shurygina, I.A. and Shurygin, M.G., RF Patent 2500104, 2013.

  5. Shurygina, I.A., Sukhov, B.G., Fadeeva, T.V., et al., Nanomedicine, 2011, vol. 7, no. 6, pp. 827–833. doi: 10.1016/j.nano.2011.03.003.

    Article  Google Scholar 

  6. Trofimov, B.A., Sukhov, B.G., Aleksandrova, G.P., et al., Dokl. Akad. Nauk, 2003, vol. 393, no. 5, p. 634.

    Google Scholar 

  7. Singh, S.C., Mishra, S.K., Srivastava, R.K., and Gopal, R., J. Phys. Chem. C, 2010, vol. 114, no. 41, pp. 17374–17384. doi: 10.1021/jp105037w.

    Article  Google Scholar 

  8. Kostyro, V.V., Kostyro, Ya.A., Lepekhova, S.A., et al., Bull. East-Siberian Acad. Med. Sci., 2013, vol. 1, pp. 106–110.

    Google Scholar 

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Correspondence to I. A. Shurygina.

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Original Russian Text © I.A. Shurygina, L.V. Rodionova, M.G. Shurygin, B.G. Sukhov, S.V. Kuznetsov, L.G. Popova, N.N. Dremina, 2015, published in Izvestiya Rossiiskoi Akademii Nauk. Seriya Fizicheskaya, 2015, Vol. 79, No. 2, pp. 280–282.

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Shurygina, I.A., Rodionova, L.V., Shurygin, M.G. et al. Using confocal microscopy to study the effect of an original pro-enzyme Se/arabinogalactan nanocomposite on tissue regeneration in a skeletal system. Bull. Russ. Acad. Sci. Phys. 79, 256–258 (2015). https://doi.org/10.3103/S1062873815020276

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  • DOI: https://doi.org/10.3103/S1062873815020276

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