Skip to main content
SpringerLink
Log in

Study of the possibility of the production and separation of the 18F radioisotope at electron accelerators

  • Physics of Atom Nuclei and Elementary Particles
  • Published:
Moscow University Physics Bulletin Aims and scope

Abstract

The possibility of production and separation of the 18F medical radioisotope at a race-track microtron with an accelerated electron energy of 55 MeV in the 23Na(γ, αn) photonuclear reaction is studied. Ion-exchange chromatography is used to separate 18F from irradiated NaOH targets.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. A. H. Becquerel, Compt. Rend. Acad. Sci. 122, 420 (1896).

    Google Scholar 

  2. M. Curie, Compt. Rend. Acad. Sci. 126, 1101 (1898).

    Google Scholar 

  3. M. Curie, Radioactiivity (Moscow, 1960) [in Russian].

    Google Scholar 

  4. F. Joliot, Chemical evidence of the transmutation of elements, 1935. http://www.nobelprize.org/nobel_prizes/chemistry/laureates/1935/joliot-fred-lecture.pdf; I. Joliot-Curie, Artificial production of radioactive ele-ments, 1935. http://www.nobel_prizes.org/nobel_prizes/chemistry/laureates/1935/joliot-curie-lecture.html/

    Google Scholar 

  5. Isotopes for Medicine and the Life Sciences, Ed. by F. J. Adelstein and F. J. Manning, (National Academy, Washington, D.C., USA, 1995).

    Google Scholar 

  6. B. L. Zhuikov, Appl. Radiat. Isotopes 84, 48 (2014).

    Article  Google Scholar 

  7. T. J. Ruth, B. D. Pate, R. Robertson, and J. K. Porter, Int. J. Appl. Radiat. Isotopes, Pt. B: Nucl. Med. Biol. 16, 323 (1989); T. J. Ruth, Nucl. Phys. News Int. 23 (2), 30 (2013).

    Article  Google Scholar 

  8. Principles of Nuclear Medicine Ed. by Z. Wagner, J. W. Szabo, and J. W. Buchanan, (W. B. Saunders, Philadelphia, 1995).

    Google Scholar 

  9. Tables of Isotopes Ed. by C. M. Lederer and V. S. Shirley, 7th ed., (Wiley, New York, 1978).

    Google Scholar 

  10. L. P. Ekstrom and R. B. Firestone, www Tables of Radioactive Isotopes. LBNL Isotopes Project (LUNDS Univ., 1999). http://ie.lbl.gov/toi/

    Google Scholar 

  11. H. N. Wagner, J. W. Buchanan, and M. N. Maisey, Clinical positron emission tomography, in Clinical Nuclear Medicine, Ed. by M. N. Maisey, K. E. Britton, and B. D. Collier, (Chapman and Hall, London, 1998).

    Google Scholar 

  12. M. J. Welch, Production of radioisotopes for biomedical studies using photonuclear reactions, Proc. Int. Conf. on Photonuclear Reactions and Applications Livermore, USA, 1973.

    Google Scholar 

  13. A. Donnerhack and E. L. Sattler, Int. J. Appl. Radiat. Isotopes 31, 279 (1980).

    Article  Google Scholar 

  14. M. Yagi and R. Amano, Int. J. Appl. Radiat. Isotopes 31, 559 (1980).

    Article  Google Scholar 

  15. M. van der Leij, B. W. van Halteren, and G. A. Brinkman, Int. J. Appl. Radiat. Isotopes 36, 717 (1985).

    Article  Google Scholar 

  16. N. I. Aizatskii, N. P. Dikii, A. N. Dovbnya, et al., Vopr. At. Nauki Tekhn. Ser.: Yad.-Fiz. Issled. 50(5), 169 (2008).

    Google Scholar 

  17. C. Ross, R. Galea, P. Saul, et al., Phys. Canada 66, 19 (2010). http://www.cap.ca/sites/cap.ca/files/article/1278/Janl0-Offprint-Ross.pdf

    Google Scholar 

  18. L. Z. Dzhilavyan, A. I. Karev, and V. G. Raevskii, On possibilities of radioisotope production with the help of photonuclear reactions for nuclear medicine on 55 MeV divided microtron, Preprint Inst. Nuclear Res. Russ. Acad. Sci., no. 1268/2010no. 1268/2010 (Moscow, 2010) [in Russian].

    Google Scholar 

  19. L. Z. Dzhilavyan, A. I. Karev, and V. G. Raevsky, Phys. At. Nucl. 74, 1690 (2011).

    Article  Google Scholar 

  20. S. S. Belyshev, L. Z. Dzhilavyan, A. N. Ermakov, B. S. Ishkhanov, V. V. Khankin, V. I. Shvedunov, A. I. Karev, and V. G. Raevsky, Moscow Univ. Phys. Bull. 67, 246 (2012).

    Article  ADS  Google Scholar 

  21. S. S. Belyshev, B. S. Ishkhanov, A. S. Kurilik, L. Z. Dzhilavyan, A. N. Ermakov, V. V. Khankin, A. A. Kuznetsov, V. I. Shvedunov, and K. A. Stopani, Bull. Russ. Acad. Sci. Phys. 77, 480 (2013).

    Article  Google Scholar 

  22. R. A. Aliev, S. S. Belyshev, L. Z. Dzhilavyan, et al., Experimental study of possibilities of 18F, 67Cu, and 177Lu production for nuclear medicine on electron accelerators, Preprint Inst. Nuclear Res. Russ. Acad. Sci., no. 1340/2013 (Moscow, 2013) [in Russian].

    Google Scholar 

  23. A. I. Karev, A. N. Lebedev, V. G. Raevsky, et al., Proc. 22nd Russ. Particle Accelerator Conf. RuPAC-2010 (2010).

    Google Scholar 

  24. S. M. Seltzer and M. J. Berger, Nucl. Instrum. Methods 12(1), 95 (1985).

    Article  Google Scholar 

  25. S. Agostinelli, J. Allison, K. Amako, J. Apostolakis, H. Araujo, P. Arce, M. Asai, D. Axen, S. Banerjee, G. Barrand, F. Behner, L. Bellagamba, J. Boudreau, L. Broglia, A. Brunengo, H. Burkhardt, S. Chauvie, J. Chuma, R. Chytracek, and G. Cooperman, Nucl. Instr. Meth. Phys. Res. A 506, 250 (2003).

    Article  ADS  Google Scholar 

  26. L. Pages, E. Bertel, H. Joffre, and L. Sklavenitis, Energy Losses, Trajectories, and Stopping Power for 10 keV to 100 MeV Electrons in Simple Elements and Some Chemical Compounds. Rapport CEA-R-3942, Centre d’Etudes Nucleares de Saclay, Saclay, 1970.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Skobel’tsyn Institute of Nuclear Physics, Moscow State University, Moscow, 119991, Russia

    R. A. Aliev, B. S. Ishkhanov, V. V. Khankin & V. I. Shvedunov

  2. Department of Physics, Moscow State University, Moscow, 119991, Russia

    S. S. Belyshev & B. S. Ishkhanov

  3. Institute for Nuclear Research, Russian Academy of Sciences, Moscow, 117312, Russia

    L. Z. Dzhilavyan

Authors
  1. R. A. Aliev
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. S. Belyshev
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. L. Z. Dzhilavyan
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. B. S. Ishkhanov
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. V. V. Khankin
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. V. I. Shvedunov
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to R. A. Aliev.

Additional information

Original Russian Text © R.A. Aliev, S.S. Belyshev, L.Z. Dzhilavyan, B.S. Ishkhanov, V.V. Khankin, V.I. Shvedunov, 2014, published in Vestnik Moskovskogo Universiteta. Fizika, 2014, No. 3, pp. 29–32.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Aliev, R.A., Belyshev, S.S., Dzhilavyan, L.Z. et al. Study of the possibility of the production and separation of the 18F radioisotope at electron accelerators. Moscow Univ. Phys. 69, 233–236 (2014). https://doi.org/10.3103/S0027134914030023

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.3103/S0027134914030023

Keywords

Search

Navigation