All age groups are at risk of contracting and dying of Coronavirus disease (COVID-19). However, older people and those  with underlying conditions, comorbidities and disability levels are at higher risk of developing a serious illness, especially those living in enclosed spaces such as nursing homes and care centers, are more vulnerable to getting this disease, which can become fatal during this pandemic. Other reasons that make them more susceptible include population density, sharing equipment, poor public health measurements and infection controlling and close contact with roommates, which may all these factors increase the transmission rate and risk of infection. Therefore, we aimed to investigate the outbreak of COVID-19 in a chronic psychiatric rehabilitation center called Behboud center in Hamadan, west of Iran. It is a rehabilitation center with 85 women clients and 16 staff.